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Fungal Lactase

Also known as: Lactase, β-galactosidase, Kluyveromyces lactis lactase, Aspergillus niger lactase, Fungal Lactase

Overview

Fungal lactase is an enzyme supplement derived from microorganisms like *Kluyveromyces lactis* or *Aspergillus niger*. It is primarily used to aid in the digestion of lactose in individuals with lactose intolerance. Lactase breaks down lactose, a sugar found in milk and dairy products, into glucose and galactose, which are more easily absorbed by the body. This enzymatic action helps to alleviate common symptoms of lactose intolerance, such as bloating, gas, and diarrhea. Fungal lactase is favored for its stability and effectiveness in hydrolyzing lactose. It is available in various forms, including capsules, tablets, and chewable formulations, making it a convenient option for managing lactose intolerance. Research supports its efficacy, with numerous studies demonstrating its ability to reduce symptoms and improve the quality of life for those with lactose intolerance.

Benefits

Fungal lactase primarily reduces the symptoms of lactose intolerance, including bloating, gas, and diarrhea, by improving lactose digestion. Studies have shown a significant reduction in hydrogen breath test results and symptom scores following lactase supplementation. It is particularly beneficial for individuals with primary or secondary hypolactasia. Some research suggests that lactase supplementation may enhance calcium absorption from dairy products, although more research is needed to confirm this effect. The benefits are typically observed shortly after consuming lactase with dairy products, providing rapid relief from lactose intolerance symptoms. High-quality evidence, including systematic reviews and randomized controlled trials, supports the use of fungal lactase for managing lactose intolerance.

How it works

Fungal lactase works by hydrolyzing lactose into its constituent monosaccharides, glucose and galactose, in the small intestine. This enzymatic action occurs in the gastrointestinal tract, specifically targeting lactose molecules present in ingested dairy products. By breaking down lactose into simpler sugars, lactase facilitates their absorption into the bloodstream, preventing the undigested lactose from fermenting in the colon. This fermentation process is what leads to the characteristic symptoms of lactose intolerance, such as gas, bloating, and diarrhea. Fungal lactase acts directly on lactose in the gut, and no systemic absorption of the enzyme itself is required for its function.

Side effects

Fungal lactase is generally considered safe for most individuals. Common side effects are rare, but some people may experience mild gastrointestinal upset, such as nausea or abdominal discomfort. There are no known significant drug interactions associated with fungal lactase. Contraindications are also rare, but individuals with known allergies to fungal-derived products should exercise caution. Special populations, including infants and pregnant or breastfeeding women, can generally use fungal lactase safely, but consulting with a healthcare provider is recommended. Overall, fungal lactase has a favorable safety profile, with minimal reported adverse effects when used as directed.

Dosage

The minimum effective dose of fungal lactase is typically around 3000-6000 IU per serving, but the optimal dosage varies based on the lactose content of the dairy products being consumed. It is recommended to take lactase immediately before or with meals containing dairy. The enzyme is available in various forms, including capsules, tablets, and chewable forms, allowing for flexible administration. There is no established maximum safe dose, but high doses are generally well-tolerated. Since lactase acts directly in the gut, absorption factors are not a primary concern. The dosage should be adjusted based on individual tolerance and the severity of lactose intolerance symptoms.

FAQs

When should I take fungal lactase?

Fungal lactase should be taken immediately before or while consuming foods or beverages containing lactose to help digest the lactose content and prevent symptoms.

Is fungal lactase safe for everyone?

Fungal lactase is generally safe, but individual tolerance may vary. Those with known allergies to fungi should exercise caution. Consult a healthcare provider if you have concerns.

How does fungal lactase work?

Fungal lactase breaks down lactose into glucose and galactose in the gut, making these simpler sugars easier to absorb and preventing the symptoms of lactose intolerance.

Is fungal lactase a cure for lactose intolerance?

No, fungal lactase is not a cure. It aids in digesting lactose, reducing symptoms, but lactose intolerance is a condition where the body doesn't produce enough lactase naturally.

How much fungal lactase should I take?

Dosage varies based on the lactose content of the food. A typical dose is 3000-6000 IU per serving, but adjust based on individual needs and product instructions.

Research Sources

https://pmc.ncbi.nlm.nih.gov/articles/PMC4923703/ – This systematic review and meta-analysis examines lactose maldigestion in individuals with inflammatory bowel diseases (IBD). It highlights the prevalence of lactose maldigestion among IBD patients and discusses various management strategies, including lactase supplementation, to alleviate symptoms and improve quality of life. The review underscores the importance of tailored approaches to manage lactose intolerance in this specific population.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4942986/ – This study compares the efficacy of different lactase formulations in reducing symptoms of lactose intolerance. The findings indicate that all tested lactase products were effective in alleviating symptoms, although the efficacy varied depending on the source and dosage of the lactase. The research suggests that individual responses to different lactase formulations may vary, highlighting the need for personalized approaches to lactose intolerance management.
https://pubmed.ncbi.nlm.nih.gov/38426798/ – This meta-analysis investigates the effects of lactase supplementation on infant colic. The results showed mixed outcomes, with some trials reporting a reduction in crying duration among infants receiving lactase. However, the overall evidence remains inconclusive, suggesting that further research is needed to determine the effectiveness of lactase supplementation for managing infant colic.
https://pubmed.ncbi.nlm.nih.gov/30462373/ – This study investigates the effect of galacto-oligosaccharides (GOS) and lactase co-administration on lactose intolerance. The results suggest that GOS may enhance the effectiveness of lactase in reducing lactose intolerance symptoms. This indicates a potential synergistic effect between prebiotics like GOS and lactase supplementation for improving lactose digestion and tolerance.
https://www.cambridge.org/core/journals/journal-of-dairy-research/article/fermented-foods-and-probiotics-an-approach-to-lactose-intolerance/77AD1896FA744AA7453AE047FD85BD17 – This review discusses the role of fermented foods and probiotics in managing lactose intolerance. It highlights that certain fermented dairy products and probiotic strains can aid in lactose digestion by providing exogenous β-galactosidase activity. The review suggests that incorporating these dietary components may offer a complementary approach to lactase supplementation for individuals with lactose intolerance.