Get Your Personalized Supplement StackSupplement Stack Quiz

Fragrant Angelica

Also known as: Maodanggui, Angelica biserrata, Chongchi Maodanggui, Fragrant Angelica, Angelica pubescens

Overview

Angelica pubescens and Angelica biserrata are medicinal herbs from the Angelica genus, traditionally used in Chinese medicine for their anti-inflammatory and analgesic properties. The roots are particularly valued for their aromatic compounds, including coumarins and volatile oils. These plants are commonly utilized to alleviate rheumatic arthritis, headaches, and general inflammation. While there's substantial research in traditional contexts, the scientific literature lacks systematic reviews and meta-analyses confirming efficacy and safety in Western medicine. The primary forms of these supplements are dried roots and extracts.

Benefits

The primary evidence-backed benefits of Angelica pubescens and biserrata include analgesic and anti-inflammatory effects, particularly relevant for conditions involving pain and inflammation. Clinical studies suggest efficacy in treating rheumatic diseases and headaches, with some evidence indicating influence on the central nervous nervous system and cardiovascular health. While the strength of evidence is limited primarily to traditional use and pharmacological studies, higher-quality clinical trials are necessary to substantiate these claims. The specific quantification of benefits remains under-explored in the literature, highlighting a need for further research.

How it works

The active compounds like coumarins and polyene-alkynes in Angelica species may inhibit the COX-1 enzyme involved in the inflammatory response, thereby potentially reducing pain and inflammation. These compounds could also modulate neurotransmitter activity relevant to pain perception, indicating a dual action on both inflammation and central nervous system pathways. However, detailed mechanisms and bioavailability in humans remain inadequately studied.

Side effects

Angelica pubescens and biserrata are generally considered safe when used in traditionally recommended doses. However, comprehensive safety data are lacking. Common side effects are not well-documented, but allergic reactions or gastrointestinal discomfort may occur in a small percentage of users. Rarely reported side effects are unspecified. Caution should be exercised due to potential drug interactions with anticoagulants or anti-inflammatory medications, primarily due to the coumarin content. Pregnant or breastfeeding women should avoid use as safety data in these populations is insufficient, and individuals with bleeding disorders should consult healthcare professionals before use.

Dosage

Traditionally, Angelica pubescens is used in doses ranging from 3-10 grams per day. However, specific dosage guidelines are not well-established in Western literature due to the lack of clinical studies. The maximum safe dose also remains undefined. Typically, the supplement is administered in the form of dried roots or extracts. Timing and absorption factors need further exploration, as they are not well-characterized in current research. As with any herbal product, consulting a healthcare provider prior to use is advised.

FAQs

Is Angelica pubescens safe to use?

Generally safe when used traditionally, but caution is advised due to potential drug interactions and a lack of safety data in pregnancy.

What are the benefits of using Fragrant Angelica?

Mainly used for its analgesic and anti-inflammatory effects, particularly in treating rheumatic pain and headaches.

How should I take Angelica pubescens?

Typically taken as dried roots or extracts, following traditional guidelines. Consult a healthcare provider for personalized advice.

Can Fragrant Angelica replace conventional medicine?

No, it should not be seen as a substitute for conventional medical treatment; always consult a healthcare professional.

Are there any side effects?

Potential side effects may include allergic reactions or gastrointestinal issues, but these are not well-documented.

Research Sources

https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2020.00335/full – This review covers the botany, traditional use, and pharmacology of Angelica pubescens, emphasizing its anti-inflammatory and analgesic properties while calling for more rigorous pharmacological studies and safety assessments.
https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2020.600249/full – This study discusses the medicinal properties and genetic diversity of Angelica biserrata, underscoring its significance in herbal medicine, though lacking direct clinical trial data.
https://www.healthline.com/health/dong-quai-ancient-mystery – While focused on Dong Quai (*Angelica sinensis*), this article highlights the importance of traditional uses of Angelica species and the need for further scientific research to substantiate health claims.
https://academic.oup.com/jxb/advance-article/doi/10.1093/jxb/erae392/7756692 – This article discusses the biological and chemical diversity of Angelica plants, though lacking specific clinical data or trials relevant to Fragrant Angelica.
https://www.researchgate.net/publication/361636884_Biological_and_Chemical_Diversity_of_Angelica_archangelica_L-Case_Study_of_Essential_Oil_and_Its_Biological_Activity – This research focuses on the essential oil and biological activities of Angelica archangelica without directly addressing Angelica pubescens or biserrata, needing further investigation for direct applicability.