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Eurypeptides

Also known as: Eurypeptides, Bioactive peptides from Eurycoma longifolia, Tongkat Ali peptides

Overview

Eurypeptides are bioactive peptides derived from *Eurycoma longifolia* (Tongkat Ali), a plant native to Southeast Asia. They are primarily known for their potential role in enhancing libido, improving fertility, and increasing testosterone levels, although most research focuses on *Eurycoma longifolia* extracts rather than isolated Eurypeptides. These peptides are believed to influence hormone levels, potentially enhancing sexual function and fertility. However, the exact mechanisms are not yet fully understood or well-documented in peer-reviewed literature. *Eurycoma longifolia* is available in various forms, including capsules, tablets, and powders, often marketed as a natural testosterone booster and aphrodisiac. Research on Eurypeptides specifically is limited, with most studies focusing on the effects of *Eurycoma longifolia* as a whole.

Benefits

Direct evidence on the benefits of isolated Eurypeptides is limited. However, studies on *Eurycoma longifolia* extracts suggest potential benefits for improving libido and testosterone levels, particularly in individuals with hypogonadism. A clinical trial involving 320 men with late-onset hypogonadism showed a significant increase in testosterone levels after one month of *Eurycoma longifolia* supplementation, although the study lacked a placebo group. Some research also indicates that *Eurycoma longifolia* may have anxiolytic effects and improve stress levels, which could indirectly support sexual health. The effect sizes for Eurypeptides specifically are not well-documented, and benefits from *Eurycoma longifolia* extracts are typically observed over several weeks to months.

How it works

The precise mechanism of action for Eurypeptides is not fully elucidated. It is hypothesized that Eurypeptides may increase testosterone levels by enhancing the activity of enzymes involved in androgen synthesis, although this is not definitively proven in peer-reviewed literature. They are believed to interact with the endocrine system, particularly affecting testosterone production and regulation. However, the specific molecular targets and biological pathways through which Eurypeptides exert their effects remain largely unknown. Further research is needed to clarify the exact mechanisms by which Eurypeptides influence hormonal balance and sexual function.

Side effects

The safety profile of isolated Eurypeptides is not well-documented. However, *Eurycoma longifolia* extracts, which contain Eurypeptides, are generally considered safe when used at recommended dosages. High doses of *Eurycoma longifolia* (e.g., above 1200 mg/kg in rats) have been shown to cause liver changes. Potential drug interactions include reduced bioavailability of certain medications like propranolol when taken concurrently with *Eurycoma longifolia*. Due to limited research, caution is advised for individuals with pre-existing medical conditions or those taking medications. Specific contraindications for Eurypeptides are not well-established. More research is needed to fully assess the potential side effects and safety considerations associated with Eurypeptides.

Dosage

There is no established minimum effective dose or optimal dosage range specifically for Eurypeptides. Typically, *Eurycoma longifolia* extracts are used in doses ranging from 100 to 200 mg per day. High doses of *Eurycoma longifolia* should be avoided due to potential liver changes observed in animal studies. The timing of administration is not specified in the available literature. *Eurycoma longifolia* is often used as part of a concentrated extract. Further research is needed to determine specific dosage recommendations for Eurypeptides and to assess factors affecting their absorption and bioavailability.

FAQs

What are Eurypeptides?

Eurypeptides are bioactive peptides derived from *Eurycoma longifolia* (Tongkat Ali), known for their potential to enhance libido and testosterone levels. However, research is limited, and most studies focus on *Eurycoma longifolia* extracts.

Are Eurypeptides safe?

*Eurycoma longifolia* extracts, which contain Eurypeptides, are generally considered safe at recommended doses. High doses may cause liver changes. Consult a healthcare provider before use, especially if you have medical conditions or take medications.

How should I take Eurypeptides?

There are no specific guidelines for Eurypeptides. Typically, *Eurycoma longifolia* extracts are used at 100-200 mg per day. Follow product label instructions and consult a healthcare provider for personalized advice.

What results can I expect from taking Eurypeptides?

Potential benefits include improved libido and increased testosterone levels, particularly in individuals with hypogonadism. However, individual results may vary, and more research is needed to confirm these effects.

Research Sources

https://examine.com/supplements/tongkat-ali/research/ – Examine.com provides a comprehensive overview of the research on Tongkat Ali, including its effects on testosterone, fertility, and overall health. It summarizes various studies and clinical trials, offering insights into the potential benefits and limitations of Tongkat Ali supplementation. The resource highlights the need for more high-quality research to fully understand the effects of Tongkat Ali.
https://pubmed.ncbi.nlm.nih.gov/26365449/ – This study investigates the effect of *Eurycoma longifolia* extract on stress hormones and psychological mood state in moderately stressed subjects. The results indicate that Tongkat Ali may help protect the body from the adverse effects of chronic stress, sleep deprivation, and exercise, potentially improving overall well-being. The research suggests that Tongkat Ali could be a beneficial supplement for managing stress and improving hormonal balance.
https://www.mdpi.com/2076-3417/14/11/4372 – This systematic review and meta-analysis evaluates the efficacy of *Eurycoma longifolia* for improving erectile function. The review includes multiple studies and assesses the overall quality of evidence supporting the use of Tongkat Ali for this purpose. The findings suggest that *Eurycoma longifolia* may have a positive impact on erectile function, but further research is needed to confirm these results.
https://pubs.acs.org/doi/10.1021/acsomega.2c06340 – This study investigates the traditional uses, phytochemistry, and pharmacological properties of *Eurycoma longifolia*. It provides an overview of the various bioactive compounds found in the plant and their potential health benefits. The research highlights the importance of further studies to validate the traditional uses and explore the full therapeutic potential of *Eurycoma longifolia*.
https://www.semanticscholar.org/paper/An-Evidence-Based-Systematic-Review-of-Tongkat-Ali-Ulbricht-Conquer/efce2ca8125997cfee4f5e440538d0bc5993d2b6 – This systematic review provides an evidence-based assessment of the efficacy and safety of Tongkat Ali. It examines the available clinical trials and preclinical studies to determine the potential benefits and risks associated with its use. The review emphasizes the need for more rigorous research to fully understand the effects of Tongkat Ali and to establish clear guidelines for its use.