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Endura Shot

Also known as: Endura Shot, Nitrate, NO3-, L-Citrulline, Beta-Alanine, Tyrosine, Dietary Nitrate

Overview

Endura Shot is a branded dietary supplement designed to enhance endurance exercise performance. It typically combines dietary nitrate, L-citrulline, and beta-alanine, sometimes including tyrosine. Dietary nitrate, often sourced from beetroot or leafy greens, is converted to nitric oxide, improving blood flow and oxygen efficiency. L-citrulline, found in watermelon, boosts nitric oxide production, supporting vasodilation. Beta-alanine, present in meat and fish, increases muscle carnosine, buffering muscle acidity. Tyrosine may enhance neurotransmitter function. Endura Shot is used by athletes to delay fatigue and improve exercise capacity, delivered as a liquid shot for rapid absorption. Research support is strong for individual ingredients, especially nitrate and beta-alanine.

Benefits

Dietary nitrate improves endurance by increasing power output, time to exhaustion, and distance traveled, while decreasing oxygen consumption during submaximal exercise. L-citrulline enhances nitric oxide production, potentially improving blood flow and reducing fatigue. Beta-alanine supplementation improves maximal intensity exercise performance, particularly in efforts lasting 1-4 minutes. Tyrosine may improve endurance through enhanced neurotransmitter synthesis and reduced fatigue under stress. Studies, including meta-analyses, support these benefits, particularly for nitrate and beta-alanine. The effects of Endura Shot are most pronounced in trained athletes engaged in high-intensity endurance activities.

How it works

Endura Shot's ingredients work through several mechanisms. Dietary nitrate converts to nitric oxide (NO), a vasodilator that improves blood flow, reduces oxygen cost, and enhances mitochondrial efficiency. L-citrulline is a precursor to arginine, which is then converted to NO, supporting vasodilation and muscle oxygenation. Beta-alanine increases muscle carnosine levels, buffering hydrogen ions during high-intensity exercise, delaying muscle fatigue. Tyrosine supports the synthesis of catecholamines, potentially improving cognitive function and endurance under stress. These combined effects enhance exercise capacity and reduce fatigue.

Side effects

Endura Shot is generally safe when used within recommended doses. Beta-alanine may cause paresthesia (tingling sensation) in some users. No significant adverse events have been reported in high-quality trials for nitrate or citrulline supplementation. Caution is advised for individuals taking medications affecting blood pressure or nitric oxide pathways. Endura Shot is contraindicated for individuals with hypotension or those on nitrate medications. Limited data are available for pregnant women, children, or individuals with chronic diseases. It's important to consult with a healthcare provider before using Endura Shot, especially if you have underlying health conditions or are taking medications.

Dosage

Effective doses of dietary nitrate range from 300 to 600 mg, taken 2-3 hours before exercise. L-citrulline is typically dosed at 6-8 grams acutely before exercise. Beta-alanine requires chronic supplementation of 4-6 grams per day over at least 4 weeks to significantly increase muscle carnosine levels. Nitrate and citrulline are often taken acutely before exercise, while beta-alanine requires chronic loading. Liquid shots like Endura Shot facilitate rapid absorption of nitrate and citrulline. It is important not to exceed recommended dosages to minimize potential side effects.

FAQs

Is Endura Shot effective for endurance?

Yes, primarily due to nitrate and citrulline content improving blood flow and exercise efficiency, supported by research.

How soon before exercise should it be taken?

Approximately 2-3 hours before for nitrate; beta-alanine requires daily use over weeks for optimal effect.

Are there side effects?

Mild tingling from beta-alanine is common; otherwise, it is generally well tolerated at recommended doses.

Can it replace training?

No, Endura Shot is an adjunct to training, enhancing performance but not a substitute for consistent exercise.

Research Sources

https://pubmed.ncbi.nlm.nih.gov/34243756/ – A systematic review and meta-analysis (Lansley et al., 2021) of 73 RCTs (n=1061) found that nitrate supplementation significantly improved power output, time to exhaustion, and distance traveled during endurance exercise, while decreasing oxygen consumption. The study indicated no effect on VO2max or blood lactate levels, suggesting benefits are related to exercise efficiency rather than maximal aerobic capacity. The evidence was rated as high-quality with a low risk of bias.
https://www.tandfonline.com/doi/full/10.1080/15502783.2023.2209056 – A systematic review and meta-analysis on citrulline (2023) showed that acute citrulline ingestion had ergogenic effects on endurance performance in young, healthy adults. The study suggests that these effects are likely due to enhanced nitric oxide production and vasodilation, which improve exercise capacity. The effect sizes were noted as moderate.
https://journals.humankinetics.com/view/journals/ijsnem/34/6/article-p397.xml – A systematic review and meta-analysis on beta-alanine (2024) found that chronic beta-alanine supplementation (4-6 g/day for ≥4 weeks) significantly improved maximal and average power output in trained athletes during high-intensity exercise. The study reported consistent effects across studies with low heterogeneity, supporting the use of beta-alanine to enhance high-intensity exercise performance.
https://pubmed.ncbi.nlm.nih.gov/27600147/ – This study investigates the effects of tyrosine supplementation on cognitive and physical performance under stress. While not directly about Endura Shot, it provides context for one of its potential ingredients, suggesting possible benefits in endurance performance through enhanced neurotransmitter synthesis and reduced fatigue.
https://www.tandfonline.com/doi/abs/10.1080/02640414.2024.2309434 – This research explores the impact of beta-alanine on exercise performance. Although the abstract is provided, accessing the full text would provide a more detailed understanding of the methodology and specific findings related to beta-alanine's effects on power output and endurance.