Dgl
Also known as: Deglycyrrhizinated Licorice, DGL, Licorice root
Overview
Deglycyrrhizinated Licorice (DGL) is an extract of licorice root (*Glycyrrhiza glabra*) with glycyrrhizin removed to minimize potential side effects. It is primarily used as an herbal supplement to support digestive health, particularly for conditions like acid reflux and functional dyspepsia. DGL is known for its protective effects on the mucosal lining of the digestive tract, helping to soothe and protect the esophagus and stomach. It is available in various forms, including chewable tablets, capsules, and powders. Research on DGL is moderate, with some clinical trials and observational studies suggesting benefits, but more rigorous trials are needed for definitive conclusions. The quality of available evidence is variable, but it generally supports the use of DGL for mild digestive discomfort.
Benefits
DGL may help reduce symptoms of acid reflux by increasing mucus production, which protects the esophagus from acidic damage. Some studies suggest benefits in treating functional dyspepsia. Research indicates that adults with acid reflux may benefit from DGL supplementation, with benefits potentially observed within a few weeks of consistent use. While specific effect sizes are not well-documented, studies suggest clinical significance in reducing heartburn symptoms. More rigorous trials are needed to confirm these benefits and determine the optimal dosage and duration of treatment.
How it works
DGL is thought to enhance mucus production in the stomach and esophagus, providing a protective barrier against acid. This action primarily interacts with the gastrointestinal system. While the specific molecular targets are not well-defined, flavonoids present in DGL may contribute to its beneficial effects. By increasing mucus production, DGL helps to protect the esophageal lining from damage caused by stomach acid, thereby reducing symptoms of heartburn and acid reflux. Specific data on the absorption and bioavailability of DGL is limited.
Side effects
DGL is generally considered safe when the glycyrrhizin content is minimized (less than 0.5%). Common side effects are rarely reported, likely due to the removal of glycyrrhizin, which is responsible for many of the adverse effects associated with whole licorice root. Uncommon and rare side effects are not well-documented. Potential interactions with medications affecting the gastrointestinal system exist, although specific data is limited. Individuals with severe gastrointestinal conditions should consult a healthcare provider before use. Pregnant or breastfeeding women should also seek medical advice before using DGL. It is important to ensure that the DGL product is certified to have low glycyrrhizin levels to minimize the risk of side effects.
Dosage
The typical minimum effective dose of DGL is around 75 mg per dose, taken twice daily. Optimal dosage ranges are generally between 150-300 mg per day. The maximum safe dose is not well-defined, but high doses should be avoided. DGL is best taken before meals to aid digestion. Chewable tablets are a common form, allowing the supplement to mix with saliva and coat the esophagus. Specific absorption factors are not well-studied. There are no documented required cofactors. It is important to follow the recommended dosage and consult with a healthcare provider if you have any concerns.
FAQs
What is DGL used for?
DGL is often used for digestive issues like acid reflux. It helps protect the lining of the esophagus and stomach from acid damage, reducing heartburn symptoms.
Is DGL safe?
DGL is generally safe when glycyrrhizin levels are low. It's important to choose products certified to have low glycyrrhizin content to minimize potential side effects.
When should I take DGL?
DGL is best taken before meals. This allows it to mix with saliva and coat the esophagus, providing a protective barrier against stomach acid.
How long does it take for DGL to work?
Many people experience a reduction in heartburn symptoms within a few weeks of consistent use. Individual results may vary, so it's important to be patient.
Will DGL cause the same side effects as licorice candy?
DGL is less likely to cause side effects similar to whole licorice root because glycyrrhizin, the compound responsible for many side effects, has been removed.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/29433679/ – This study investigates the effects of licorice consumption on various health parameters. While not specifically focused on DGL, it provides insights into the broader effects of licorice, including potential benefits for weight management and metabolic changes. The research highlights the need for further studies specifically on DGL to isolate its unique effects.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC8703329/ – This article discusses the potential health benefits of licorice and its bioactive compounds. It explores the mechanisms through which licorice may exert its effects, including anti-inflammatory and antioxidant properties. The review emphasizes the importance of considering the specific form of licorice (e.g., DGL vs. whole licorice) when evaluating its health effects.
- https://www.medicalnewstoday.com/articles/dgl-for-acid-reflux – This article provides an overview of DGL and its potential benefits for acid reflux. It explains how DGL may help protect the esophageal lining and reduce heartburn symptoms. The article also highlights the importance of choosing DGL products with low glycyrrhizin content to minimize the risk of side effects.
- https://www.lifeextension.com/wellness/supplements/dgl-supplements – This resource discusses the use of DGL supplements for digestive health. It provides information on the potential benefits of DGL, including its ability to soothe and protect the gastrointestinal tract. The article also offers guidance on dosage and usage recommendations for DGL supplements.
- https://foodguides.com/blogs/from-the-experts/examining-licorice-root-for-acid-reflux-relief – This blog post examines the use of licorice root, specifically DGL, for acid reflux relief. It explains how DGL can help reduce heartburn symptoms by promoting mucus production and protecting the esophageal lining. The article also emphasizes the importance of consulting with a healthcare professional before using DGL, especially if you have underlying health conditions.
