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Debaryomyces Hansenii

Also known as: Debaryomyces hansenii, D. hansenii

Overview

Debaryomyces hansenii is a species of yeast known for its extremophilic properties, meaning it can thrive in environments with high salt concentrations. While primarily used in aquaculture to enhance growth and feed efficiency in fish, research is exploring its potential applications in human health, particularly concerning gut health and immune responses. This yeast is capable of promoting cell proliferation and differentiation, as well as enhancing metabolic pathways. However, it's important to note that the research on D. hansenii's effects in humans is still emerging, with most evidence currently derived from animal studies. More human trials are needed to fully understand its benefits and safety profile. It is not widely recognized as a human probiotic supplement.

Benefits

In aquaculture, Debaryomyces hansenii has demonstrated the ability to enhance somatic growth and improve feed efficiency in fish. Studies suggest it may also regulate immune responses and enhance antioxidant mechanisms in fish. However, its benefits in human health are less established. One study indicated that D. hansenii may contribute to impaired intestinal mucosal healing in certain conditions, such as in mice treated with antibiotics and in patients with Crohn's disease. Therefore, while promising in aquaculture, further research is needed to determine the specific benefits and risks of D. hansenii for human consumption.

How it works

In fish, Debaryomyces hansenii promotes protein-related, sphingolipid, and thymidylate pathways, enhancing antioxidant and immune mechanisms. Its interaction with the gut microbiome in humans is not fully understood, and its specific molecular targets in human health remain undefined. Further research is needed to elucidate the precise mechanisms of action of D. hansenii in the human body.

Side effects

The overall safety assessment of Debaryomyces hansenii suggests it is generally safe in animal studies. However, human safety data is limited. Common, uncommon, and rare side effects have not been reported in available literature, and drug interactions have not been studied. There are no established contraindications. Caution is advised in individuals with compromised gut health due to the potential for impaired mucosal healing, as indicated by one study. More research is needed to fully understand the safety profile of D. hansenii in humans.

Dosage

Currently, there is no established minimum effective dose, optimal dosage range, or maximum safe dose for Debaryomyces hansenii in human use. Timing considerations, form-specific recommendations, absorption factors, and required cofactors have not been studied. Therefore, specific dosing guidelines for human consumption cannot be provided at this time.

FAQs

Is Debaryomyces hansenii safe for human consumption?

While generally safe in animal studies, human safety data is limited. Caution is advised, especially for those with compromised gut health. More research is needed.

What are the benefits of Debaryomyces hansenii for humans?

Benefits are more established in fish, where it enhances growth and immunity. In humans, its role in gut health is still under investigation, with some studies showing potential negative effects on intestinal healing.

How should Debaryomyces hansenii be administered?

Administration guidelines for human use are not established. It is primarily used in aquaculture, and its application in humans is speculative and requires further research.

Is Debaryomyces hansenii a well-recognized probiotic?

No, it is not widely recognized as a human probiotic supplement. Its primary use is in aquaculture, and more research is needed to determine its potential as a human probiotic.

Research Sources

  • https://pmc.ncbi.nlm.nih.gov/articles/PMC10329801/ – This aquaculture study found that dietary administration of *D. hansenii* enhanced somatic growth and improved feed efficiency in fish. The study highlights beneficial effects on intestinal health, suggesting a potential role for *D. hansenii* in improving fish farming practices. The research provides insights into the yeast's impact on growth and digestive health in aquatic animals.
  • https://pubmed.ncbi.nlm.nih.gov/37422657/ – This study supports the findings that dietary *D. hansenii* enhances somatic growth and improves feed efficiency in fish. It reinforces the potential of *D. hansenii* as a beneficial supplement in aquaculture. The research contributes to the growing body of evidence supporting the use of this yeast in improving fish farming outcomes.
  • https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2022.836810/full – This study investigated the effects of hydrolyzed *D. hansenii* yeast products on Atlantic salmon under hypoxia stress. The results suggest that these products have the potential to regulate stress and immune responses in fish. This research indicates a possible application of *D. hansenii* in mitigating the effects of environmental stressors on aquatic animals.
  • https://www.science.org/doi/10.1126/science.abd0919 – This study found that *D. hansenii* was found to impair intestinal mucosal healing in mice treated with antibiotics and in patients with Crohn's disease. The research suggests a potential negative impact of *D. hansenii* on gut health in certain conditions. This finding highlights the complexity of *D. hansenii*'s effects and the need for further investigation into its role in human health.

Supplements Containing Debaryomyces Hansenii

RAW Probiotis Colon Care by Garden of Life
70

RAW Probiotis Colon Care

Garden of Life

Score: 70/100
Women 50 & Wiser by Garden of Life Raw Probiotics
78

Women 50 & Wiser

Garden of Life Raw Probiotics

Score: 78/100
Men by Garden of Life Raw Probiotics
68

Men

Garden of Life Raw Probiotics

Score: 68/100
Raw Probiotic 100 Billion CFU by Wholesome Wellness
70

Raw Probiotic 100 Billion CFU

Wholesome Wellness

Score: 70/100
Women 50 & Wiser by Garden Of Life Raw Probiotics
78

Women 50 & Wiser

Garden Of Life Raw Probiotics

Score: 78/100
Men by Garden of Life Raw Probiotics
68

Men

Garden of Life Raw Probiotics

Score: 68/100
Men 50 & Wiser by Garden of Life Raw Probiotics
68

Men 50 & Wiser

Garden of Life Raw Probiotics

Score: 68/100
Vaginal Care by Garden of Life Raw Probiotics
88

Vaginal Care

Garden of Life Raw Probiotics

Score: 88/100
Women by Garden of Life Raw Probiotics
88

Women

Garden of Life Raw Probiotics

Score: 88/100
Women 50 & Wiser by Garden of Life Raw Probiotics
68

Women 50 & Wiser

Garden of Life Raw Probiotics

Score: 68/100
Ultimate Care by Garden of Life Raw Probiotics
87

Ultimate Care

Garden of Life Raw Probiotics

Score: 87/100