Corn Syrup Solids
Also known as: Corn syrup solids, maltodextrin, dextrose equivalents, maltobionic acid, Corn Syrup Solids
Overview
Corn syrup solids are dehydrated forms of corn syrup, produced through the enzymatic hydrolysis of corn starch. They are primarily composed of glucose polymers, including maltodextrins and other oligosaccharides. Widely used in the food industry as sweeteners, bulking agents, and carriers, they also serve as a carbohydrate energy source in supplements. These solids are characterized by their high glycemic index, water solubility, bland taste, and stability in powdered form. While generally considered a caloric sweetener and carbohydrate source, specific health effects depend on their composition and the context of their use. Research on corn syrup solids themselves is moderate, with most studies focusing on the metabolic effects of high glycemic carbohydrates or specific derivatives like maltobionic acid.
Benefits
Corn syrup solids, in their basic form, offer no direct nutritional benefits beyond providing a carbohydrate energy source. However, specific formulations containing maltobionic acid have shown promising effects on bone health. A randomized, double-blind, placebo-controlled crossover study involving 40 healthy adults demonstrated that daily ingestion of 4 g of corn syrup solids containing maltobionic acid calcium salt for 4 weeks significantly improved bone resorption markers (DPD and u-NTx) (p < 0.05). This suggests a potential benefit for bone metabolism in healthy adults. While statistically significant, the clinical relevance of these findings requires further investigation. The effects were observed within 4 weeks of consistent daily intake. No broad claims for other populations or conditions can be made based on current evidence.
How it works
The primary mechanism of action for corn syrup solids is as a rapidly digestible carbohydrate, providing quick energy through glucose. When formulated with maltobionic acid, the mechanism shifts. Maltobionic acid, a component of some corn syrup solids, is believed to inhibit osteoclast differentiation. Osteoclasts are cells responsible for bone resorption, meaning their inhibition can lead to reduced bone breakdown. This interaction primarily affects bone metabolism pathways, potentially modulating the balance of bone remodeling. While maltobionic acid is absorbed and exerts systemic effects, the specific molecular targets within the osteoclast differentiation pathways are not yet fully elucidated.
Side effects
Corn syrup solids are generally recognized as safe (GRAS) as a food additive. In controlled trials, specifically those involving corn syrup solids containing maltobionic acid, no adverse events were reported at the studied doses. Common side effects are not documented in high-quality studies, nor are uncommon or rare side effects. There are no known significant drug interactions. Contraindications are not established, but caution is advised for individuals requiring strict glycemic control due to the high carbohydrate content and glycemic index of corn syrup solids. Diabetics, in particular, should monitor their intake closely as it can significantly raise blood glucose levels.
Dosage
For bone metabolism effects, a minimum effective dose of 4 g/day of corn syrup solids containing maltobionic acid was found to be effective in a clinical study. Optimal dosage ranges beyond this specific application are not well established. There is no specific maximum safe dose for corn syrup solids, though typical dietary exposure can be higher. However, moderation is advised, especially for individuals with metabolic disorders, due to its high glycemic load. The studied form was a powdered form, taken daily, with timing relative to meals not specified. Corn syrup solids are rapidly digested to glucose, and maltobionic acid has demonstrated bioavailability.
FAQs
Is corn syrup solids beneficial beyond energy supply?
Standard corn syrup solids primarily provide carbohydrates for energy. However, specific formulations containing maltobionic acid have shown preliminary evidence for improving bone metabolism markers.
Are corn syrup solids safe?
Yes, corn syrup solids are generally recognized as safe (GRAS) as a food additive and are considered safe at typical consumption levels. No adverse events have been reported in studies.
Can it affect blood sugar?
Yes, as a high glycemic carbohydrate, corn syrup solids can rapidly raise blood glucose levels. Individuals with diabetes or those managing blood sugar should monitor their intake.
How soon do benefits appear?
In a study focusing on bone metabolism, effects from corn syrup solids containing maltobionic acid were observed after 4 weeks of daily intake.
Is it the same as high fructose corn syrup?
No, corn syrup solids are primarily composed of glucose polymers and are distinct from high fructose corn syrup, which contains a significant amount of fructose.
Research Sources
- https://onlinelibrary.wiley.com/doi/full/10.1002/fsn3.1387 – This randomized, double-blind, placebo-controlled crossover study investigated the effects of corn syrup solids containing maltobionic acid calcium salt on bone metabolism in 40 healthy adults over 4 weeks. The study found a statistically significant improvement in bone resorption markers (DPD and u-NTx) with no reported adverse events, suggesting a potential benefit for bone health.
- https://www.ahajournals.org/doi/pdf/10.1161/jaha.114.001700 – This source, likely a review or guideline from the American Heart Association, discusses the metabolic effects of sugars, including fructose, on lipid profiles and cardiovascular risk. While not directly about corn syrup solids, it highlights the broader context of carbohydrate type and dose in metabolic health, emphasizing the need for consideration of glycemic impact.
Supplements Containing Corn Syrup Solids

COMBAT PROTEIN POWDER
musclepharm®

1st Phorm PHORMULA-1 Pure Whey Protein Isolate Chocolate Milkshake Protein Powder Drink Mix
1st Phorm

MASS-TECH
MUSCLETECH

Strawberry Lemonade Infuser Drink Mix
Essential 1

BSN
Bio-Engineered Supplements & Nutrition, Inc.

SYNTHA-6® ULTRA PREMIUM PROTEIN MATRIX
BSN®

VANILLA BEAN PROTEIN SHAKE
PROFLEX

Homestyle Chick'n Noodle Soup Mix
OPTAVIA®

Vectron Ultra Bio-Active Fractionated Protein Matrix
Vectron