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Coffee Berry Concentrate

Also known as: Coffee berry, Coffee fruit, Coffee cherry, Whole coffee fruit concentrate (WCFC), Coffee Berry Extract

Overview

Coffee berry extract is derived from the fruit of the coffee plant, specifically *Coffea arabica* and *Coffea canephora*. It is rich in polyphenols, particularly chlorogenic acid, and contains a small amount of caffeine. This extract is primarily used to support brain health, enhance cognitive function, and potentially aid in managing metabolic conditions like diabetes and obesity. The research on coffee berry extract is still in the early stages, with evidence emerging primarily from small-scale clinical trials and animal studies indicating its potential benefits. The quality of the available evidence is variable, necessitating larger studies to validate these findings.

Benefits

Coffee berry extract has demonstrated several potential benefits supported by varying degrees of evidence: 1) It significantly increases plasma BDNF levels, crucial for neuronal health, with a 91% increase observed 60 minutes post-consumption of 100 mg of whole coffee fruit concentrate. 2) High doses (up to 1100 mg) have shown improvements in specific cognitive tasks, despite inconsistent findings. 3) Antioxidant activity has been observed through DPPH and ABTS scavenging activities, indicating potential protection against oxidative stress. 4) Animal studies suggest anti-obesity and anti-diabetic effects, targeting liver glucose metabolic processes. Older adults may benefit particularly from these effects as a means of supporting cognitive function and overall brain health.

How it works

The exact mechanisms of coffee berry extract are not fully elucidated, but it is known to stimulate the release of BDNF from various cells, enhancing neuronal functioning. Additionally, its high polyphenol content, notably chlorogenic acid, may play a role in improving glucose metabolism and lipid regulation. The extract's antioxidant properties also contribute to its effects, potentially mitigating oxidative stress in the body. This supplement interacts with the nervous system, thereby enhancing cognitive functions, alongside influencing metabolic pathways related to energy usage and storage.

Side effects

Coffee berry extract is generally considered safe when consumed in moderation, though comprehensive safety data is still lacking. Common side effects have not been well documented, with no significant adverse reactions reported in the reviewed human studies. However, individuals sensitive to caffeine should exercise caution due to the extract's low caffeine content. Potential interactions with medications affecting glucose and lipid metabolism may exist, though specific interactions are not thoroughly described. Pregnant or breastfeeding women and individuals with chronic health conditions should consult healthcare providers before use, as a precautionary measure.

Dosage

The effective dosage range for coffee berry extract is between 100 mg to 1100 mg per day, with a minimum effective dose of 100 mg shown to increase BDNF levels. Doses as high as 1100 mg have been employed in studies with noted cognitive benefits, though additional investigations are necessary to establish optimal ranges. The absorption is generally good but may depend on the specific form used (capsules, tablets, liquid extracts). There are no established maximum safe dosages, as clinical studies have not reported significant adverse effects at these levels. Timing of intake does not appear essential, as cognitive benefits and changes in BDNF levels can occur relatively quickly after ingestion.

FAQs

Is coffee berry extract safe to use?

Yes, coffee berry extract is generally safe, but individuals sensitive to caffeine should consider its caffeine content.

How should I take coffee berry extract?

Timing is not critical, but expect effects on BDNF levels shortly after ingestion, typically within 60 minutes.

What benefits can I expect?

Users may experience increases in BDNF levels, potential cognitive enhancements, and metabolic health benefits, albeit based on limited evidence.

Can I replace my regular coffee with coffee berry extract?

No, coffee berry extract is not a substitute for coffee and contains mainly polyphenolic benefits rather than significant caffeine.

Research Sources

https://www.scirp.org/journal/paperinformation?paperid=36447 – This study showed that a single 100 mg dose of whole coffee fruit concentrate significantly increased plasma BDNF levels in a young, healthy cohort. It highlighted the need for further investigation into its potential cognitive benefits, but the small sample size represents a limitation.
https://pubmed.ncbi.nlm.nih.gov/37299382/ – This randomized study assessed the effects of coffee berry extract on cognitive performance. Although it involved various dosages, low and moderate doses did not reveal beneficial effects on mood or cognition, necessitating a cautious interpretation of the results.
https://pubmed.ncbi.nlm.nih.gov/34380382/ – The randomized trial examined the acute effects of high dosages of coffee berry extract on cognitive tasks. Results indicated possible alerting effects, but the benefits remained limited, suggesting further research is required to clarify its cognitive impact.