Clovinol Clove Extract
Also known as: Syzygium aromaticum, Clovinol, Eugenol extract, Clove essential oil, Clove Extract
Overview
Clove extract is derived from the dried flower buds of the clove tree, *Syzygium aromaticum*, and is rich in polyphenols, prominently eugenol. Historically utilized in both culinary and medicinal contexts, it is noted for antioxidant, anti-inflammatory, antiviral, and anticancer properties. Its acquisition of popularity in the supplement domain is largely attributed to research indicating benefits for metabolic health, specifically its role in regulating blood sugar levels and aiding weight management. Classified as a polyphenol-rich herbal supplement, clove extract’s efficacy is backed by moderate to advanced research maturity, showing significant potential in helping prevent chronic diseases and improving overall dietary patterns.
Benefits
Research indicates that clove extract provides meaningful benefits, particularly in metabolic health. Clinical studies report a 21.5% reduction in postprandial blood glucose in healthy individuals and a 27.2% decrease in prediabetics after 30 days of administration. Its effects on weight management are also notable; studies suggest it inhibits fatty acid synthase and improves lipid profiles. Antioxidant and anti-inflammatory properties may contribute to reduced risks of chronic diseases such as cancer and cardiovascular disorders. Furthermore, clove extract is being investigated for its anti-tumor effects, suggesting potential as an adjunct therapy in enhancing chemotherapy outcomes.
How it works
Clove extract functions through multiple biological mechanisms: It enhances glucose uptake in muscle cells while concurrently inhibiting gluconeogenesis in the liver, thereby decreasing glucose production. Additionally, it suppresses digestive enzymes like alpha-glucosidase and alpha-amylase, reducing carbohydrate-derived glucose release. The inhibition of fatty acid synthase plays a key role in lipid metabolism, thereby supporting weight management. The active compounds, notably eugenol and eugenyl acetate, interact intricately with metabolic pathways to elicit these effects.
Side effects
Clove extract is generally safe when consumed in moderate amounts, with minor side effects reported. No significant adverse reactions have been extensively documented in available studies, but caution is advised for individuals on antidiabetic medications due to possible interactions affecting glucose or lipid metabolism. Specific contraindications remain poorly defined; however, individuals with allergies to clove or similar spices should exercise caution. Pregnant and lactating women are encouraged to consult healthcare professionals due to insufficient safety data in these groups. The lack of extensive documentation on uncommon side effects necessitates cautious use, highlighting the need for further safety profile investigations.
Dosage
The minimally effective dosage of clove extract is 250 mg per day, beneficial for lowering postprandial blood sugar levels. While an optimal dosage range has yet to be firmly established, this amount is generally considered effective and safe for most individuals. No maximum safe dosage has been clearly defined, though caution at higher doses is advised to mitigate risks of interactions and side effects. It is recommended to consume clove extract post-meal to manage blood sugar spikes effectively. Clove extract is readily available in capsules or tablet forms, with its bioavailability deemed adequate; however, further research could enhance understanding of its absorption dynamics. No specific cofactors are necessary for its action.
FAQs
Is clove extract safe?
Clove extract is generally safe for most people, but potential interactions with medications should be considered; consult with a healthcare provider if unsure.
When should I take clove extract?
It's advisable to take clove extract after meals to help manage postprandial blood sugar levels.
What results can I expect?
Users may expect significant reductions in after-meal blood sugar, especially in prediabetic individuals, with effects observable within the first month.
Can clove extract replace diabetes medication?
Clove extract should not replace standard diabetes treatment; it is intended as a complementary approach.
Research Sources
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796613/ – This study evaluated the effects of clove extract on metabolic parameters in prediabetic individuals, demonstrating a significant reduction in postprandial blood glucose levels and improved lipid profiles after a 30-day regimen.
- https://www.sciencedirect.com/science/article/pii/S0378874118308567 – Animal studies highlighted the lipid-lowering and weight management effects of clove extract, attributing these benefits to its inhibition of fatty acid synthase and enhancements in metabolic health metrics.
- https://pubmed.ncbi.nlm.nih.gov/24164737/ – This review underlined the antioxidant and anti-inflammatory properties of clove extract, linking these with reduced risk factors for various chronic diseases, including cancer and cardiovascular issues.
