Clematis Armandii Stem Extract
Also known as: Evergreen Clematis, Armand's Clematis, Clematis armandii
Overview
Clematis armandii stem extract is derived from the plant *Clematis armandii*, which is traditionally utilized in Chinese medicine. It is primarily recognized for its anti-inflammatory properties and its components, particularly lignans, which are known for their potential anti-neuroinflammatory activities. Although commonly used in herbal medicine, the current state of research surrounding *Clematis armandii* is limited, relying mostly on traditional applications and basic scientific studies. There is a notable absence of rigorous clinical trials that could validate its benefits or define its efficacy across various health conditions, indicating a low level of evidence maturity for this herbal supplement.
Benefits
The primary reported benefit of *Clematis armandii* stem extract is its anti-inflammatory effects, which may extend to neuroinflammation; however, the evidence is largely derived from basic research rather than comprehensive clinical trials. No significant secondary benefits have been established, and the extract has not been well-studied within specific populations, making the strengths of the effects and clinical significance indeterminate. Due to the absence of clinical data, effect size quantification and time course of benefits remain unknown.
How it works
The proposed mechanism of action for *Clematis armandii* involves its anti-inflammatory effects, potentially modulating immune responses. While the interaction with body systems, specifically the nervous and immune systems, is suggested, the precise biological pathways and molecular targets remain inadequately defined. Additionally, detailed studies on absorption and bioavailability have not been conducted.
Side effects
The safety profile of *Clematis armandii* is largely unestablished, as there is minimal documentation of side effects or adverse reactions in controlled studies. While generally regarded as safe in traditional uses, the lack of rigorous safety evaluations means that caution is warranted. Presently, there are no known drug interactions or contraindications, nor specific safety guidelines for populations such as pregnant women, children, or the elderly. Overall, the lack of adverse effects data must be recognized as a significant gap in the research.
Dosage
There are no established dosing guidelines for *Clematis armandii* stem extract, including minimum effective doses, optimal dosage ranges, or maximum safe doses. The timing of administration and any form-specific recommendations remain undefined, and factors influencing absorption have not been systematically studied. Without clinically validated dosages, individuals may encounter uncertainty regarding effective usage and safety thresholds.
FAQs
What are the practical usage concerns of *Clematis armandii*?
Due to the lack of clinical evidence, it is challenging to recommend *Clematis armandii* for specific health conditions.
Is *Clematis armandii* safe to use?
Safety data are limited, so it is advisable to approach its use with caution.
What is the expected timing for results from *Clematis armandii*?
The timeline for expected results remains unknown due to the absence of clinical trials.
Are there common misconceptions about *Clematis armandii*?
It may be mistakenly viewed as having broader health benefits than currently supported by research.
Research Sources
- https://www.extrica.com/article/16271 – This study highlights the presence of lignans in *Clematis armandii* and their observed anti-neuroinflammatory properties, although significant limitations include the lack of human clinical trials.
- https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.802624/full – This comparative pharmacognostic study identifies unique vascular bundle structures in *Clematis armandii* and notes the presence of beta-sitosterol but focuses primarily on botanical identification.
- https://experts.umn.edu/en/publications/effectiveness-of-nutritional-ingredients-on-upper-gastrointestina – This review discusses various herbal ingredients, including *Clematis armandii*, used for diverse health conditions; however, the evidence often remains largely anecdotal and lacks rigorous clinical validation.
