Citrus Limonium Extract
Also known as: Citrus limon, Lemon, Citron, Lemon fruit extract, *Citrus limon*
Overview
*Citrus limon* is a citrus species known for its fruit, lemon, which is rich in bioactive compounds such as flavonoids, essential oils, and carotenoids. These compounds contribute to its use in traditional medicine for their antioxidant and anti-inflammatory effects. While typically consumed in culinary applications, it is also incorporated into dietary supplements and nutraceuticals. The research on *Citrus limon* is moderately developed, indicating promising but not yet conclusive health benefits primarily due to limited human clinical trials and variability in study designs. Its extracts are commonly utilized for their potential to mitigate oxidative stress and inflammation in various health contexts.
Benefits
The primary benefits of *Citrus limon* include its potent antioxidant and anti-inflammatory properties, which can aid in reducing oxidative stress and inflammation, particularly beneficial for athletes after strenuous physical activities. Evidence indicates that lemon seed extracts possess neuro-modulatory effects conducive to neurological health. Furthermore, emerging data suggest potential improvements in lipid profiles and cardiovascular health; however, these benefits require further empirical support due to the insufficient number of high-quality human studies. The effect sizes are yet to be robustly quantified, emphasizing a need for more focused research.
How it works
*Citrus limon* exerts its effects primarily through pathways associated with antioxidant and anti-inflammatory responses, potentially modulating NF-kB signaling pathways. The bioactive flavonoids present in the extracts are believed to interact with enzymes involved in lipid metabolism and inflammation, thereby influencing cardiovascular health and reducing oxidative stress. Interaction with central nervous system pathways has been noted as potentially advantageous for neuroprotection.
Side effects
Generally regarded as safe when consumed in food amounts, *Citrus limon* does present some risk factors. Common side effects are not well documented; however, potential mild adverse effects may include gastrointestinal upset and allergic reactions, occurring in a minority of users. Rare side effects remain unidentified due to lack of robust data. Caution is recommended for individuals on blood-thinning medications or those managing diabetes due to possible interactions with flavonoid content. Pregnant or breastfeeding women should consult health care providers before use, as long-term safety data in these populations are lacking.
Dosage
Dosage for *Citrus limon* has not been firmly established. Generally, it is consumed in dietary amounts with specific supplemental dosages varying widely, often falling between 500 mg to 2000 mg per day of extract. Due to individual variability in absorption, the general recommendation is to adhere to typical dosages found in food. As the maximum safe dosage is unspecified, ensuring proper identification of the product and consulting health professionals is advisable, particularly for concentrated extracts or essential oils.
FAQs
What are the main uses of *Citrus limon* supplements?
They are primarily used for their antioxidant and anti-inflammatory effects, which can aid in recovery post-exercise.
Is *Citrus limon* safe to take?
*Citrus limon* is considered safe for most individuals when used in dietary amounts; however, allergies and interactions should be monitored.
What is the recommended dosage for *Citrus limon* extracts?
There is no established dosage, but common use ranges between 500 mg to 2000 mg per day, depending on the extract formulation.
Can *Citrus limon* help with weight loss?
While some effects on lipid profiles are noted, more research is needed to confirm weight loss benefits specifically.
Is *Citrus limonium* a recognized species?
No, *Citrus limonium* is not recognized, and benefits are attributed to *Citrus limon*.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/35164478/ – This systematic review discusses the antioxidant and anti-inflammatory properties of *Citrus limon* extracts, highlighting their potential benefits in reducing oxidative stress across various studies. Limitations include high heterogeneity and a scarcity of robust human trials.
- https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.822678/full – An *in vivo* study demonstrates the neuro-modulatory effects of *Citrus limon* seed extracts in Swiss albino mice. While the findings are promising, they underscore the need for additional research in human populations.
- https://academic.oup.com/nutritionreviews/article/82/9/1292/7272715?login=false – A meta-analysis investigating various *Citrus* products and their effects on dyslipidemia indicates potential benefits for lipid management; however, the evidence is complicated by high heterogeneity among included studies.
