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Chinese Hawthorn Fruit Extract

Also known as: Crataegus pinnatifida Bge., Chinese Hawthorn, Shan Zha, Crataegus pinnatifida

Overview

Chinese Hawthorn Fruit Extract is derived from the fruit of *Crataegus pinnatifida*, a plant traditionally used in Chinese medicine, primarily for cardiovascular health. It is rich in polyphenols, including procyanidins and flavonoids, which are believed to contribute to its beneficial effects. The extract is used to support heart health, manage hyperlipidemia (high cholesterol), and potentially aid in the treatment of atherosclerosis. Research on Chinese Hawthorn is considered to be at a moderate level, with some clinical trials and meta-analyses available, though more rigorous studies are needed to confirm its efficacy. The quality of available evidence is variable, with some studies showing promise but also exhibiting methodological limitations. It is available in various forms, including capsules and tablets, often containing standardized extracts.

Benefits

Chinese Hawthorn Fruit Extract has been shown to lower serum lipid levels, including total cholesterol and triglycerides, while increasing high-density lipoprotein (HDL) cholesterol. These effects are attributed to its anti-oxidative and anti-inflammatory properties. Some studies suggest potential benefits in improving cardiovascular health, particularly in reducing symptoms of chronic heart failure and atherosclerosis. It may be beneficial for individuals with hyperlipidemia or those at risk of cardiovascular disease. While hawthorn extracts show promise, they are generally less effective than conventional lipid-lowering drugs in reducing low-density lipoprotein (LDL) cholesterol. Benefits may be observed within several weeks to months of consistent use.

How it works

Chinese Hawthorn Fruit Extract influences lipid metabolism, exerts anti-oxidative effects, and protects vascular endothelial function. It acts on the cardiovascular system by improving lipid profiles and enhancing blood circulation. The key active components are oligomeric procyanidins and flavonoids. While the exact mechanisms are still being investigated, it is believed that these compounds interact with various biological pathways involved in lipid metabolism and vascular function. Limited data is available on the absorption and bioavailability of the extract, indicating a need for further research in this area.

Side effects

Chinese Hawthorn Fruit Extract is generally considered safe, with rare adverse effects reported. The most common side effects are gastrointestinal disturbances, though these are infrequent. Drug interactions are a potential concern, particularly with cardiovascular medications, so caution is advised. Contraindications are not well-established, but it is recommended that pregnant or breastfeeding women consult healthcare providers before use. Individuals with severe cardiovascular conditions or those taking medications for heart conditions should also use it with caution. Overall, the safety profile is favorable, but awareness of potential interactions and individual sensitivities is important.

Dosage

Specific optimal dosages for Chinese Hawthorn Fruit Extract are not clearly defined. Standardized extracts are often used, but the minimum effective dose is not well-established. Consistent daily intake is recommended for potential benefits. Capsules or tablets containing standardized extracts are common forms. The maximum safe dose is not well-documented, so caution is advised against excessive intake. Bioavailability may vary, and further research is needed to determine optimal absorption factors. It is generally recommended to consult with a healthcare provider to determine the appropriate dosage based on individual health status and potential interactions with other medications.

FAQs

Is Chinese Hawthorn Fruit Extract safe to use with other medications?

It is generally safe, but potential interactions with cardiovascular drugs exist. Consult a healthcare provider before using, especially if taking other medications.

How long does it take to see results from taking this supplement?

Potential improvements in lipid profiles and cardiovascular health may be observed within several weeks to months of consistent daily use.

Can Chinese Hawthorn Fruit Extract replace my heart medication?

No, it is not a replacement for conventional medical treatment and should be used under medical supervision. It is meant to be a supplement to existing treatments.

How should I take Chinese Hawthorn Fruit Extract?

Consistent daily use is recommended. Follow the dosage instructions on the product label or as directed by your healthcare provider. Typically, it is taken in capsule or tablet form.

What are the expected benefits of taking this extract?

Potential benefits include improvements in lipid profiles and cardiovascular health. It may help lower cholesterol and triglycerides while increasing HDL cholesterol.

Research Sources

  • https://pubmed.ncbi.nlm.nih.gov/38482041/ – A meta-analysis of fourteen randomized controlled trials found that hawthorn-based medicine reduces total cholesterol and triglycerides while increasing HDL cholesterol. However, it was noted to be less effective than standard drugs in lowering LDL cholesterol. The study also highlighted methodological limitations in some of the included trials, resulting in a moderate quality assessment.
  • https://onlinelibrary.wiley.com/doi/full/10.1002%2Ffft2.413 – This review discusses the serum lipid-lowering, anti-oxidative, and cardiovascular protective properties of hawthorn extracts. While it provides a comprehensive overview of the mechanisms, it emphasizes the need for more clinical trials to validate these findings. The review serves as a theoretical basis for the potential benefits of hawthorn but lacks specific clinical data.
  • https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2020.00118/full – An animal study using rats with doxorubicin-induced inflammation found that an ethanol extract of Chinese Hawthorn reduces inflammation and oxidative stress. While the study provides insight into potential mechanisms, it is limited by its animal model and the need for human studies to confirm these effects. The findings suggest a potential role for Chinese Hawthorn in reducing inflammation, but direct human application requires further investigation.
  • https://www.aafp.org/pubs/afp/issues/2010/0215/p465.html – This article provides general information about hawthorn and its potential uses. It is a helpful resource for understanding the basics of hawthorn and its traditional applications. However, it does not provide in-depth research findings or specific details about Chinese Hawthorn Fruit Extract.
  • https://www.mdpi.com/1420-3049/17/12/14490 – This study investigates the chemical composition and potential health benefits of hawthorn. It provides valuable information about the bioactive compounds present in hawthorn and their potential mechanisms of action. However, it does not focus specifically on Chinese Hawthorn Fruit Extract or its clinical applications.