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Camu Camu Fruit Extract

Also known as: Myrciaria dubia, Camu Camu, Camucamu, Açaí do igapó

Overview

Camu Camu (*Myrciaria dubia*) is a tropical fruit native to the Amazon basin, belonging to the Myrtaceae family. It is highly regarded for its exceptionally high vitamin C content, often surpassing that of common citrus fruits. As a dietary supplement, Camu Camu is utilized for its antioxidant, anti-inflammatory, anti-hyperglycemic, and potential anti-obesity properties. The fruit is rich in bioactive compounds, including vitamins, flavonoids, and anthocyanins, contributing to its health-promoting effects. Research on Camu Camu is ongoing, with preclinical and small-scale human trials showing promising results. The fruit is available in various forms, including powders and extracts, offering a convenient way to incorporate its benefits into one's diet. While the evidence is still emerging, Camu Camu shows potential as a valuable addition to a healthy lifestyle.

Benefits

Camu Camu extract exhibits several evidence-based benefits, primarily related to its antioxidant and anti-inflammatory properties. Studies have demonstrated its ability to reduce oxidative stress and inflammatory responses. For instance, it can inhibit histamine release and reduce the expression of calcium channel proteins in mast cells, suggesting its potential as a mast cell stabilizer and anti-histamine. Animal studies have also shown improvements in lipid profiles, including reductions in glycemia, cholesterol, and triglycerides in obese rats. Additionally, there is some evidence suggesting anti-hyperglycemic effects and potential benefits for weight management, although these findings require further validation in human trials. The high vitamin C content and other bioactive compounds contribute to general health benefits, particularly in boosting the immune system and reducing oxidative stress. More human trials are needed to fully establish the clinical significance of these effects.

How it works

Camu Camu's mechanism of action is primarily attributed to its high concentration of vitamin C and other antioxidants. These compounds scavenge free radicals, reducing oxidative stress throughout the body. The extract also exhibits anti-inflammatory activity by inhibiting histamine release and reducing the expression of calcium channel proteins, thereby stabilizing mast cells and modulating inflammatory responses. Furthermore, it regulates NFAT and Nrf2 signaling pathways, which are crucial in managing oxidative stress and inflammation. By influencing these pathways, Camu Camu affects the immune and metabolic systems, contributing to its observed health benefits. The bioaccessibility of its bioactive compounds is enhanced through dehydration techniques, such as spray-drying and freeze-drying, improving its effectiveness when consumed.

Side effects

Camu Camu is generally considered safe when consumed in recommended amounts. However, due to its high vitamin C content, excessive intake can lead to gastrointestinal side effects such as nausea, diarrhea, and abdominal cramps. Individuals with conditions sensitive to high vitamin C levels, such as hemochromatosis or kidney stones, should exercise caution. Drug interactions are possible, particularly with medications affecting iron levels or those sensitive to vitamin C. Pregnant or breastfeeding women should consult healthcare providers before using Camu Camu supplements due to limited human studies. While rare side effects have not been documented, it is essential to adhere to recommended dosages to minimize potential adverse effects. It is also important to note that individual responses may vary, and any unusual symptoms should be reported to a healthcare professional.

Dosage

While specific human studies are limited, typical supplement dosages of Camu Camu range from 500 mg to 2 grams per day, often standardized to a certain percentage of vitamin C. Animal studies have used doses of 1g/kg/day of hydroalcoholic extract. Due to the high vitamin C content, it is advisable to avoid exceeding 2000 mg per day to prevent gastrointestinal side effects. Dehydrated forms like spray-dried or freeze-dried powders may offer better bioavailability. Camu Camu can be taken at any time of day as part of a daily supplement regimen. Bioaccessibility is improved when incorporated into food matrices like yogurt or juice. It is always recommended to consult with a healthcare provider to determine the appropriate dosage based on individual health status and needs.

FAQs

Is Camu Camu safe to consume?

Camu Camu is generally safe in recommended doses. However, high doses of vitamin C can cause gastrointestinal issues. Individuals with specific health conditions should consult a healthcare provider.

When is the best time to take Camu Camu?

Camu Camu can be taken at any time of day as part of a supplement regimen. There are no specific timing recommendations, but consistency is key for optimal results.

What are the expected benefits of taking Camu Camu?

Camu Camu offers antioxidant and anti-inflammatory effects. It may also improve lipid profiles and blood sugar control, but more research is needed to confirm these benefits.

Can Camu Camu replace medical treatment?

No, Camu Camu is not a substitute for medical treatment. It can be used as a complementary supplement to support overall health and well-being.

How should Camu Camu be stored to maintain its potency?

Camu Camu supplements should be stored in a cool, dry place away from direct sunlight to preserve the stability and bioactivity of its compounds.

Research Sources

https://www.scielo.br/j/rcbc/a/hG6PCLVkG4Dq6dNnSzrRfWG/?format=pdf&lang=en – This animal study investigated the effects of dietary supplementation with Camu-Camu versus sleeve gastrectomy in Wistar rats. The key findings included a significant reduction in BMI and improvements in lipid profiles in rats treated with Camu-Camu extract compared to controls, suggesting potential benefits for weight management and metabolic health.
https://www.mdpi.com/2076-3921/11/1/104 – This in vitro study examined the anti-allergic effects of *Myrciaria dubia* (Camu-Camu) fruit extract. The extract inhibited histamine release and reduced the expression of calcium channel proteins in RBL-2H3 cells, indicating potential anti-allergic properties and suggesting its use as a mast cell stabilizer.
https://www.sciencedirect.com/science/article/pii/S0963996923013686 – This study focused on the characterization and bioaccessibility assessment of bioactive compounds from Camu-Camu. The results showed that dehydration techniques, such as spray-drying and freeze-drying, improved the bioaccessibility of bioactive compounds, with better recovery percentages observed in certain food matrices, enhancing its potential for dietary applications.
https://www.healthline.com/nutrition/camu-camu – This article provides a general overview of Camu Camu, highlighting its high vitamin C content and potential health benefits. It discusses its antioxidant and anti-inflammatory properties, as well as its traditional uses and nutritional profile, offering a comprehensive introduction to the fruit.
https://www.mdpi.com/1718-7729/30/9/570 – This study investigates the impact of Camu-Camu on oxidative stress and inflammatory responses. The findings suggest that Camu-Camu regulates NFAT and Nrf2 signaling pathways, which are involved in oxidative stress and inflammatory responses, further supporting its potential health benefits.