ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Bovine Hydrolyzed Collagen Powder

Also known as: Hydrolyzed Collagen, Bovine Hydrolyzed Collagen Powder, Collagen Peptides

Overview

Bovine hydrolyzed collagen is a dietary supplement derived from bovine sources through a process called hydrolysis, which breaks down collagen into smaller peptides, enhancing its solubility and bioavailability. Primarily composed of collagen types I, II, and III, it is widely used to support skin, joint, and bone health. As a nutricosmetic, it's often incorporated into beauty and wellness routines. Research indicates that hydrolyzed collagen can improve skin hydration and elasticity, making it a popular choice for those seeking to mitigate signs of aging. While evidence is strongest for skin benefits, ongoing research explores its potential to support joint and bone health. It is available in various forms, including powders and capsules, and is generally considered safe for consumption.

Benefits

Hydrolyzed collagen is primarily known for its benefits to skin health. Studies have shown significant improvements in skin hydration and elasticity compared to placebo, with substantial effect sizes (SMD for hydration: 0.63, 95% CI 0.38, 0.88; for elasticity: 0.72, 95% CI 0.40, 1.03). Research also indicates a reduction in mean skin wrinkle value with collagen supplementation (−1.11; 95% CI −1.94, −0.28; P = 0.009). Secondary benefits include increased dermal density and reduced facial wrinkles. These benefits are particularly noted in middle-aged and older adults. Improvements are typically observed within 60 to 90 days of supplementation and may persist for a short period after cessation.

How it works

Hydrolyzed collagen works by stimulating collagen synthesis within the body. The smaller peptides are more easily absorbed and utilized by fibroblasts, the cells responsible for producing collagen. This process enhances the dermal collagen network, improving skin hydration and elasticity. Additionally, hydrolyzed collagen may influence the production of other important proteins like fibronectin and elastin. Its effects primarily target the skin, but it may also support joint and bone health through similar mechanisms of collagen synthesis.

Side effects

Hydrolyzed collagen is generally considered safe with minimal side effects. The most commonly reported side effects are rare and may include mild gastrointestinal issues in some individuals. Allergic reactions or sensitivities are possible but uncommon. Serious adverse effects are not commonly reported. There are no significant drug interactions documented, but caution is advised in individuals with severe allergies to bovine products. Pregnant or breastfeeding women should consult healthcare providers before use to ensure safety.

Dosage

The recommended dosage range for hydrolyzed collagen is typically between 5-10 grams per day. A minimum effective dose is around 5 grams per day. While a maximum safe dose is not well-defined, doses above 10 grams are less commonly studied. Consistent daily intake is recommended for optimal results. Hydrolyzed collagen is commonly available in powder or capsule form. Its bioavailability is enhanced due to the hydrolysis process, which breaks down collagen into smaller, more easily absorbed peptides. No specific cofactors are required for its absorption or efficacy.

FAQs

How long does it take to see benefits from hydrolyzed collagen?

Benefits are typically observed within 60 to 90 days of consistent daily intake. Improvements in skin hydration and elasticity are common early indicators.

Is hydrolyzed collagen safe?

Hydrolyzed collagen is generally safe for most individuals. However, those with severe allergies, especially to bovine products, should exercise caution and consult a healthcare provider.

How should I take hydrolyzed collagen?

Consistent daily intake is recommended. It can be taken in powder or capsule form, mixed with water, juice, or other beverages. Follow the dosage guidelines provided by the manufacturer or a healthcare professional.

What results can I expect from taking hydrolyzed collagen?

You can expect improvements in skin hydration and elasticity, as well as a potential reduction in the appearance of wrinkles. It supports skin health but is not a cure-all for aging.

Research Sources

  • https://pmc.ncbi.nlm.nih.gov/articles/PMC10180699/ – This systematic review and meta-analysis, encompassing 1721 patients across 26 RCTs, found that hydrolyzed collagen significantly improves skin hydration and elasticity. The studies ranged from 2 to 12 weeks in duration. The review highlights the high-quality evidence supporting the benefits of hydrolyzed collagen for skin health, while also noting variability in collagen sources and study durations as limitations.
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC10773595/ – This systematic review and meta-analysis examined various studies, including those using fish-derived collagen, and found consistent improvements in skin hydration and elasticity. The studies lasted up to 12 weeks. The review provides strong evidence for the skin rejuvenation benefits of hydrolyzed collagen, while acknowledging heterogeneity in study designs and collagen sources as limitations.
  • https://gomitasc3.com/wp-content/uploads/2023/05/Collagen-suplementation-on-skin-aging.pdf – This meta-analysis, including 1,125 participants across 19 studies, found that hydrolyzed collagen reduces signs of skin aging, including wrinkles, over a duration of up to 90 days. The analysis supports the benefits of hydrolyzed collagen for skin aging, while noting limited data on long-term effects. This research suggests that collagen supplementation can be an effective strategy for mitigating age-related skin changes.
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC8620403/ – This study investigates the effects of collagen supplementation on skin health. It provides evidence supporting the use of collagen to improve skin elasticity and hydration. The research contributes to the growing body of knowledge on the benefits of collagen for dermatological applications.
  • https://pubmed.ncbi.nlm.nih.gov/33742704/ – This study provides further evidence supporting the benefits of hydrolyzed collagen for skin health. It highlights the potential of collagen supplementation to improve various skin parameters. The research adds to the understanding of how collagen can be used to promote healthier skin.

Supplements Containing Bovine Hydrolyzed Collagen Powder

COFFEE+ Mushrooms | Collagen Protein | Nootropics by EVERYDAY DOSE
68

COFFEE+ Mushrooms | Collagen Protein | Nootropics

EVERYDAY DOSE

Score: 68/100
BOLD COFFEE+ by EVERYDAY DOSE
63

BOLD COFFEE+

EVERYDAY DOSE

Score: 63/100
BOLD COFFEE+ by EVERYDAY DOSE
68

BOLD COFFEE+

EVERYDAY DOSE

Score: 68/100

Recommended Articles

Top Bioavailable Protein Powders: A Buyer’s Guide

Top Bioavailable Protein Powders: A Buyer’s Guide

Bioavailability in protein powders is key for muscle synthesis, with whey protein leading at a 70-80% rate.

Collagen for Knee OA: Does It Help?

Collagen for Knee OA: Does It Help?

Collagen supplementation has been shown to significantly reduce knee osteoarthritis pain and improve mobility.

Best Time to Take Collagen for Optimal Results

Best Time to Take Collagen for Optimal Results

The best time to take collagen depends on your goals: morning for skin and overall wellness, and before bed for muscle and joint recovery.

Do Collagen Supplements Enhance Skin Elasticity?

Do Collagen Supplements Enhance Skin Elasticity?

Collagen supplements have been proven to enhance skin elasticity and hydration, contributing to reduced appearance of wrinkles.