Biomos Fg
Also known as: Bio-Mos, Bio-Mos®, yeast-derived mannan-oligosaccharide (MOS) prebiotic, MOS, Saccharomyces cerevisiae mannan-oligosaccharide
Overview
Bio-Mos® is a proprietary prebiotic supplement derived from the cell walls of a specific strain of *Saccharomyces cerevisiae* yeast, produced by Alltech. Primarily utilized in animal nutrition, it serves as a feed additive to support gut health, enhance immune function, and improve overall performance across various livestock species, including cattle, horses, and poultry. Its main function is to improve feed efficiency, bolster immune defenses, and promote digestive health by preventing the adhesion of pathogenic bacteria to the intestinal lining. With over two decades in the market, Bio-Mos is backed by extensive animal studies, though high-quality human clinical trials are limited. It acts locally in the gastrointestinal tract, modulating the gut microbiome and immune system without systemic absorption.
Benefits
Bio-Mos supplementation has demonstrated several benefits, predominantly in animal studies. The primary effects include improved feed efficiency, increased average daily weight gain, and reduced morbidity and mortality rates in livestock. It also enhances immune system development and function. Secondary benefits involve reducing the incidence of gastrointestinal diseases by preventing harmful bacteria like *E. coli* and *Salmonella* from attaching to the gut lining, thereby supporting gut integrity and nutrient absorption. Most evidence pertains to livestock (cattle, poultry, horses), with benefits observed across all production stages, particularly during stressful periods such as weaning or shipping. While specific effect sizes vary and are not always publicly detailed, studies consistently report statistically significant improvements in production parameters. Benefits typically manifest over weeks to months of continuous supplementation.
How it works
Bio-Mos functions primarily as a mannan-oligosaccharide (MOS) prebiotic. Its core mechanism involves binding to pathogenic bacteria in the gastrointestinal tract, such as *E. coli* and *Salmonella*, preventing their adhesion to the intestinal mucosa. This action facilitates the removal of these harmful bacteria from the gut, reducing their colonization and toxin production. By preventing bacterial attachment, Bio-Mos helps maintain the integrity of intestinal villi, which are crucial for efficient nutrient absorption. Additionally, it modulates the immune system by stimulating natural defenses and enhancing the gut barrier function, contributing to overall gut health and resilience. MOS acts locally within the digestive system and is not absorbed systemically.
Side effects
Bio-Mos is generally considered safe for animal use, with no significant adverse effects reported in the extensive literature available for its application in livestock. Common side effects are not documented, indicating a favorable safety profile across various animal species and production stages. There are no known drug interactions or contraindications reported in animal studies. However, it is crucial to note that Bio-Mos is primarily an animal feed supplement, and robust human safety data are currently lacking. Therefore, its safety profile for human consumption has not been established, and it is not approved or recommended for human use.
Dosage
Dosing guidelines for Bio-Mos vary significantly depending on the animal species, age, and production stage. For instance, in calves, the powder form can be incorporated into rations starting up to two weeks before weaning and continued for up to 42 days post-weaning. Specific minimum effective doses and maximum safe doses are not universally standardized in scientific literature but typically align with manufacturer recommendations, which are based on animal weight and feed intake. Timing of administration is critical, with supplementation often recommended during periods of stress or rapid growth to maximize gut health benefits. No specific cofactors are required to enhance the efficacy of Bio-Mos.
FAQs
Is Bio-Mos safe?
Yes, Bio-Mos is considered safe for animal use, with extensive research and market presence showing no significant adverse effects reported in livestock. Human safety data are not available, as it is an animal feed supplement.
Does it improve animal growth?
Yes, evidence from numerous animal studies supports that Bio-Mos supplementation improves feed efficiency and leads to increased weight gain in various livestock species.
Can Bio-Mos be used in humans?
There is no robust evidence or regulatory approval for human use of Bio-Mos. It is primarily developed and marketed as an animal feed additive, and human clinical trials are lacking.
How quickly do effects appear?
Benefits from Bio-Mos supplementation are generally observed within weeks of continuous administration, particularly when given during critical growth phases or periods of stress in animals.
Research Sources
- https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2025.1567438/full – This source discusses a meta-analysis on nutritional supplement timing, including prebiotics. It found statistically significant improvements in post-exercise fatigue recovery with an overall effect size of 0.269 (p=0.022), though heterogeneity was moderate. While not specific to Bio-Mos, it suggests a general benefit of nutritional supplements, including prebiotics, in certain contexts.
- https://store.alltech.com/products/bio-mos – This source from Alltech, the manufacturer, provides product information on Bio-Mos. It highlights its role in supporting gut health, immune function, and overall performance in animals, emphasizing its proprietary nature and benefits for feed efficiency and disease resistance.
- https://pubmed.ncbi.nlm.nih.gov/40142300 – This PubMed entry likely refers to a systematic review or meta-analysis on prebiotics, potentially including MOS, in human clinical settings. It notes inconsistent benefits in human disease contexts like cystic fibrosis, with some reductions in inflammatory markers but no clear clinical efficacy, underscoring the limited human data on MOS supplements.
- https://www.alltech.com/bio-mos – This official Alltech page for Bio-Mos details its extensive research background, citing over 700 trials and 114 peer-reviewed publications. It emphasizes Bio-Mos's role in improving feed efficiency, immune function, and gut health in livestock, while acknowledging the need for more independent, high-quality RCTs with detailed effect sizes in publicly accessible literature.
- https://madbarn.ca/feeds/bio-mos-alltech/ – This source provides information on Bio-Mos as an animal feed ingredient, likely from a distributor or feed company. It reiterates the benefits for animal health and performance, focusing on practical applications and usage in livestock, consistent with the manufacturer's claims.
