Bifidobacterium Longum Bl88
Also known as: *Bifidobacterium longum* Bl88, Probiotic Strain
Overview
*Bifidobacterium longum* is a species of probiotic bacteria commonly found in the human gut and utilized as a dietary supplement known for supporting gut health and enhancing immune function. Its primary applications include improving gastrointestinal health and potentially reducing the risk of certain diseases, especially in vulnerable populations like preterm infants. Research maturity surrounding *Bifidobacterium longum* is considered moderate; while a growing body of evidence supports its therapeutic benefits, the quality and outcomes of available studies vary. This strain is typically found in fermented foods and probiotic supplements, and serves to foster a healthy gut microbiome through its digestive and immunological benefits.
Benefits
*Bifidobacterium longum* offers several evidence-based benefits, notably the significant reduction in the risk of necrotizing enterocolitis (NEC) in infants, indicated by a risk ratio of 0.539 (95% CI: 0.333, 0.874), with preterm infants experiencing the greatest advantage. It also shows potential in alleviating symptoms associated with irritable bowel syndrome (IBS). Although some literature mentions weight gain in infants, findings are inconclusive, suggesting that more robust research is needed in this area. Effect sizes related to NEC reduction are compelling, and extended supplementation may be necessary to achieve observable benefits for IBS, according to existing studies.
How it works
*Bifidobacterium longum* functions primarily by modulating the gut microbiota, which supports the maintenance of barrier functions in the gastrointestinal tract and influences the immune response. It interacts closely with both the gastrointestinal and immune systems, contributing to digestive health and overall wellness. While specific molecular targets are not well-defined in current literature, it appears to affect gut epithelial cells and immune cells, enhancing the body's natural defenses and microbial balance without being absorbed in the conventional sense.
Side effects
The overall safety profile for *Bifidobacterium longum* Bl88 is generally favorable, with most studies showing no significant increase in adverse events compared to control groups. Mild gastrointestinal symptoms, such as bloating or gas, may occasionally occur but are quite rare. Serious side effects are exceptionally uncommon and not significantly different from standard controls. There are no widely reported drug interactions; however, immunocompromised individuals should exercise caution when considering probiotic supplementation.
Dosage
Recommended dosage for *Bifidobacterium longum* typically falls within the range of 10^8 to 10^9 CFU per day, although the precise minimum effective dose is not well-established and can vary depending on specific studies. Continuous supplementation is often necessary to sustain benefits, and common forms include capsules and powders. The maximum safe dose has not been definitively established, but these dosages are generally considered safe, and probiotics are designed to colonize the gut rather than being absorbed into the bloodstream.
FAQs
How should I store *Bifidobacterium longum*?
Probiotics should be stored in a cool, dry place to maintain viability and effectiveness.
Is there anyone who should avoid this probiotic?
While generally safe, individuals who are immunocompromised should consult a healthcare provider before starting any probiotic.
When is the best time to take *Bifidobacterium longum*?
Taking the probiotic with food may help enhance its survival as it passes through the stomach.
What benefits can I expect?
Research suggests notable reductions in NEC in infants and improvements in IBS symptoms for adults, though results may vary individually.
Is this strain a cure for all gut issues?
No, *Bifidobacterium longum* is not a cure-all; its efficacy can vary and it may not benefit everyone equally.
Research Sources
- https://www.mdpi.com/2304-8158/12/24/4451/review_report – This meta-analysis reviews clinical trials focusing on neonatal outcomes related to probiotic use, particularly highlighting reduced risk of necrotizing enterocolitis in preterm infants, although it identifies limitations in variability across studies.
- https://pubmed.ncbi.nlm.nih.gov/38137255/ – This systematic review synthesizes evidence from multiple studies on the impact of probiotics on IBS, demonstrating symptom improvement and quality of life enhancements among affected patients.
- https://www.microbiotajournal.com/wp-content/uploads/sites/7/2024/06/e998.pdf – General commentary on probiotic research underscores the potential benefits of strains like *Bifidobacterium longum* for gut health and immune function, advocating for more focused investigations into specific strains.
Supplements Containing Bifidobacterium Longum Bl88
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