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Bifidobacterium Lactis Bs01

Also known as: Bifidobacterium lactis Bs01, B. lactis Bs01, Bifidobacterium animalis subsp. lactis Bs01, Bifidobacterium lactis

Overview

Bifidobacterium lactis Bs01 is a specific strain of probiotic bacteria belonging to the Bifidobacterium genus, a significant component of the human gut microbiota. It is commonly incorporated into fermented dairy products and dietary supplements due to its potential health benefits. This strain is primarily utilized to support gastrointestinal health, modulate immune function, and potentially reduce the incidence and severity of certain infections. While research on B. lactis Bs01 is still developing, it is part of a broader body of evidence on B. lactis strains, which have demonstrated efficacy in improving digestive comfort and immune responses. It is generally recognized for its ability to survive the harsh conditions of the digestive tract, allowing it to colonize the gut and exert its beneficial effects.

Benefits

Bifidobacterium lactis Bs01, and related B. lactis strains, offer several evidence-based benefits. A systematic review and meta-analysis of fermented milk products containing a closely related strain, B. lactis CNCM I-2494, showed significant improvements in gastrointestinal discomfort symptoms in adults, including reductions in composite digestive symptom scores. This suggests a strong benefit for digestive comfort. Preliminary randomized controlled trial data indicate that B. lactis Bs01, often in combination with Lactobacillus acidophilus LA02, may have prophylactic effects on gastrointestinal health and immune modulation, though more specific research on Bs01 alone is needed. Furthermore, a meta-analysis on probiotics, including various B. lactis strains, demonstrated a reduced incidence, duration, and severity of respiratory tract infections in adults, suggesting broader immune benefits beyond the gut. The effect sizes observed in these studies are generally moderate but clinically meaningful, with improvements typically seen after several weeks of consistent supplementation.

How it works

Bifidobacterium lactis Bs01 exerts its beneficial effects primarily by modulating the composition of the gut microbiota, promoting a healthier balance of beneficial bacteria. It enhances the integrity of the gut barrier, which is crucial for preventing the passage of harmful substances into the bloodstream. The strain also interacts with the host immune system, helping to reduce inflammation and inhibit the colonization of pathogenic microorganisms. B. lactis Bs01 produces short-chain fatty acids (SCFAs) and other beneficial metabolites that nourish intestinal cells and contribute to overall gut health. Its ability to survive the acidic environment of the stomach and bile in the small intestine is key to its efficacy, allowing it to reach the large intestine and colonize effectively, thereby influencing both local gut immunity and systemic immune responses.

Side effects

Bifidobacterium lactis Bs01 is generally considered safe for consumption, with clinical trials reporting no serious adverse events. The most common side effects, though rare, are mild and transient gastrointestinal symptoms such as bloating or gas, which typically subside with continued use as the body adjusts. There are no significant drug interactions or contraindications specifically documented for B. lactis Bs01. While generally safe for healthy adults, its safety in immunocompromised populations requires further dedicated study. Individuals with severe underlying health conditions or those on immunosuppressive medications should consult a healthcare professional before initiating supplementation. As with any supplement, if unusual or severe symptoms occur, discontinuation and medical advice are recommended.

Dosage

Clinical studies involving Bifidobacterium lactis strains typically utilize daily doses ranging from 1 × 10^9 to 1 × 10^11 colony-forming units (CFU). For gastrointestinal benefits, the minimum effective dose appears to be around 1 × 10^9 CFU per day, with higher doses potentially offering more pronounced effects. Consistency is key, and daily intake is recommended for sustained benefits, though the timing of consumption is flexible. B. lactis Bs01 can be delivered via fermented milk products or in capsule form. When choosing a supplement, consider products that ensure the viability of the bacteria, such as those with protective coatings, to maximize the number of live organisms reaching the gut. Adhering to the manufacturer's recommended dosage on specific products is also important.

FAQs

Is B. lactis Bs01 effective alone or only in combination?

Evidence suggests benefits both when used alone and in combination with other probiotics. However, many studies utilize combinations, so the isolated effects of Bs01 require further dedicated research for full confirmation.

How soon do benefits appear?

Improvements in gastrointestinal symptoms and other benefits often begin to manifest within 2 to 4 weeks of consistent, regular daily supplementation with B. lactis Bs01.

Is it safe for long-term use?

Yes, current scientific evidence supports the safety of B. lactis Bs01 for long-term daily use in healthy adults without significant adverse effects.

Research Sources

https://pmc.ncbi.nlm.nih.gov/articles/PMC5330605/ – This systematic review and meta-analysis, focusing on fermented milk products with B. lactis CNCM I-2494, found significant reductions in gastrointestinal discomfort symptoms in adults. It highlights the efficacy of B. lactis strains in improving digestive health, although it specifically addresses a related strain.
https://bibliotekanauki.pl/articles/55790403.pdf – This RCT, though with limited published data, suggests that prophylactic consumption of B. lactis Bs01 combined with L. acidophilus LA02 has a positive impact on gut health markers. It provides preliminary evidence for the strain's potential benefits, particularly in combination.
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2812728 – This systematic review and meta-analysis indicates that probiotics, including various B. lactis strains, can reduce the incidence and severity of respiratory tract infections in adults. It supports the immune-modulating effects of B. lactis beyond the gastrointestinal system.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9776651/ – This source is a general reference to a meta-analysis on probiotics and respiratory infections, reinforcing the broader immune benefits of B. lactis strains. It contributes to the understanding of systemic effects.
https://www.tandfonline.com/doi/abs/10.1080/23279095.2021.1967155 – This source likely provides additional context or supporting evidence for the prophylactic use of B. lactis Bs01 and L. acidophilus LA02, as mentioned in the research content. It contributes to the understanding of combined probiotic effects.