Bifidobacterium Infantis Bi02 Dsm 24687
Also known as: *Bifidobacterium infantis* BI02, *Bifidobacterium infantis*, *Bifidobacterium infantis* DSM 24687, *Bifidobacterium infantis* BI02 DSM 24687
Overview
*Bifidobacterium infantis* BI02 DSM 24687 is a probiotic strain primarily associated with gut health, particularly in infants. This species is naturally found in healthy human gut flora, especially in breastfed infants, where it plays a crucial role in digestive health by metabolizing human milk oligosaccharides. Its unique ability to produce bile salt hydrolase suggests it may also have applications in promoting cardiometabolic health. Despite emerging evidence supporting its benefits, particularly in preterm infants, research specific to the BI02 strain is limited, necessitating more clinical investigations to fully understand its efficacy and safety profile.
Benefits
The key benefits of *Bifidobacterium infantis* BI02 include a significant reduction in necrotizing enterocolitis (NEC) and late-onset sepsis (LOS) in preterm infants, with a relative risk (RR) of 0.38, indicating a substantial protective effect. Furthermore, there are potential benefits for cardiometabolic health due to its bile salt hydrolase activity. Although the most substantial evidence is centered on preterm infants, its role in augmenting gut health is recognized more broadly. Systematic reviews point towards an improved overall gut microbiota composition, though specific impact timelines for BI02 remain underdocumented.
How it works
*Bifidobacterium infantis* BI02 primarily functions by utilizing human milk oligosaccharides, aiding in its colonization of the gut and promoting a healthy gut microbiota balance. Its bile salt hydrolase activity may also enhance lipid metabolism by breaking down bile salts, thus influencing lipid absorption and overall cardiovascular health. This strain's ability to produce beneficial metabolites contributes to a conducive environment for other probiotic organisms, enhancing the gut's ecological balance.
Side effects
Generally, *Bifidobacterium infantis* BI02 is well-tolerated and considered safe for use. Common side effects may include mild gastrointestinal issues such as bloating and gas. Less common side effects are not well-documented. Caution is advised for immunocompromised individuals, as there exists a potential risk for systemic infections. No significant drug interactions have been reported, but critically ill patients should use this probiotic with caution. Additionally, as with all probiotics, adverse effects may vary with individual tolerance and health conditions, warranting attentive monitoring during use.
Dosage
While the minimum effective dose of *Bifidobacterium infantis* BI02 has not been firmly established, typical recommendations for probiotics range from 1-10 billion CFU per day. It is suggested to take this probiotic with food to enhance its survival through the stomach. Exact dosages may vary based on formulation (single strain vs. blends) and specific health goals. There are currently no defined upper limits for the safe consumption of this strain, though users are encouraged to consult health professionals for personalized advice.
FAQs
How should I store *Bifidobacterium infantis* BI02?
Store in a cool, dry place to maintain the viability of the probiotics.
Is it safe to take if I am immunocompromised?
Generally safe, but consult with a healthcare provider before use due to potential risks.
When is the best time to take this probiotic?
It is best taken with meals to promote better survival through the digestive system.
What results can I expect from using this probiotic?
Expected benefits include improved gut health and potential support for cardiometabolic functions.
Can this probiotic replace medical treatment?
No, it should not replace medical treatment; consult a healthcare provider for health issues.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/37460707/ – This systematic review discusses the efficacy of *Bifidobacterium infantis* in reducing necrotizing enterocolitis (NEC) incidence among preterm infants. It establishes a significant relative risk reduction, supporting the strain's clinical advantage in neonatal health.
- https://dsld.od.nih.gov/ingredient/Bifidobacterium%20infantis%20BI02%20DSM%2024687 – The source provides an overview of *Bifidobacterium infantis* BI02, highlighting its role in gut microbiota health and potential applications in improving cardiometabolic conditions.
- https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2018.00124/full – This meta-analysis emphasizes the importance of strain-specific effectiveness of probiotics and the role of *Bifidobacterium infantis* in managing various health outcomes, underscoring the need for further strain-specific research.
- https://www.probiotical.com/en/products/probiotic-bifidobacterium-infantis-bi02/ – The webpage details *Bifidobacterium infantis* BI02's characteristics and applications, specifically how this strain can be utilized to support digestive health and potentially mitigate disease in vulnerable populations.
- https://eurospechim.com/wp-content/uploads/pdf/strains_catalogue_v5_2021.pdf – This document catalogues various strains, including *Bifidobacterium infantis* BI02, providing insights into their functionalities and therapeutic applications in probiotic formulations.
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