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Bifidobacteria Lactis

Also known as: Bifidobacteria Lactis, Bifidobacterium lactis, Bifidobacterium animalis subspecies lactis, *Bifidobacterium lactis*

Overview

*Bifidobacterium lactis* is a prevalent probiotic bacteria found in fermented foods like yogurt and dietary supplements. This strain is recognized for its potential benefits in promoting gastrointestinal health and supporting immune function. It exhibits resilience by surviving stomach acid and effectively colonizing the intestines. Research indicates that *B. lactis* can alleviate gastrointestinal discomfort and enhance immune response. The body of evidence is steadily expanding, with systematic reviews and meta-analyses supporting its efficacy in various populations, particularly healthy adults and preterm infants. Overall, it is considered safe for most individuals and provides accessible means of incorporation into the diet through supplements and fermented dairy products.

Benefits

{"primary":[{"benefit":"Gastrointestinal Health","evidence_strength":"High-quality evidence from meta-analysis","description":"Significant reduction in gastrointestinal discomfort in healthy adults."},{"benefit":"Defecation Frequency","evidence_strength":"Moderate evidence","description":"May improve defecation frequency in healthy adults with a measured increase."}],"secondary":[{"benefit":"Weight Gain in Infants","evidence_strength":"Moderate-quality evidence from RCT","description":"Shown to enhance body weight in preterm infants post-antibiotic treatment."}],"population_specific":[{"population":"Healthy Adults","benefits":"Improvement in gastrointestinal symptoms and enhanced defecation frequency."},{"population":"Preterm Infants","benefits":"Increased weight gain and better fecal pH and immune markers."}]}

How it works

*Bifidobacterium lactis* works by colonizing the gut and enhancing gut barrier function while modulating the immune system. It metabolizes dietary fibers to produce short-chain fatty acids, which foster a conducive environment for beneficial bacteria and inhibit pathogenic microbes. Its interaction with the gastrointestinal and immune systems contributes to the maintenance of a balanced gut microbiota, promoting overall gut health.

Side effects

{"general_safety":"Considered safe for most individuals with minimal side effects.","common_side_effects":"May cause mild gastrointestinal issues such as bloating or gas, typically transient.","rare_side_effects":"Rare cases of probiotic-associated infections reported in immunocompromised individuals.","drug_interactions":"No significant drug interactions noted.","contraindications":"Caution advised for severely immunocompromised individuals; consult a healthcare provider.","special_population":"Precaution is recommended for critically ill patients or those with compromised immune systems."}

Dosage

{"minimum_effective_dose":"1 to 10 billion CFU per day.","optimal_dosage":"1 to 10 billion CFU daily shown effective in studies.","maximum_safe_dose":"Doses up to 20 billion CFU have been used without adverse effects.","timing":"Best taken with meals to improve survival through the stomach.","forms":"Available in capsules, powders, and fermented foods.","absorption_factors":"Taking with food enhances viability and absorption."}

FAQs

How should I store probiotics?

Store in a cool, dry place to ensure the viability of the bacteria.

Is *Bifidobacterium lactis* safe for everyone?

Generally safe; however, consult with a healthcare provider if you are immunocompromised.

When is the best time to take probiotics?

Taking probiotics with meals may optimize their effectiveness.

When can I expect to see results?

Gastrointestinal improvements may be noticeable within weeks of supplementation.

Are all probiotics the same?

No, different strains have specific effects; hence, strain-specific benefits matter.

Research Sources

https://pubmed.ncbi.nlm.nih.gov/28286561/ – This meta-analysis involving 598 adults demonstrated significant improvements in gastrointestinal discomfort through *Bifidobacterium lactis* CNCM I-2494 supplementation. Results indicate an odds ratio of 1.48 (95% CI 1.07-2.05), signifying notable efficacy in the population studied.
https://pubmed.ncbi.nlm.nih.gov/18552710/ – This randomized controlled trial with 69 preterm infants showed that supplementation with *Bifidobacterium lactis* Bb12 led to increased body weight and improved fecal markers, highlighting its potential benefits in vulnerable populations.
https://pubmed.ncbi.nlm.nih.gov/34918142/ – This systematic review consolidated various studies to examine the impact of *Bifidobacterium lactis* on gastrointestinal symptoms, revealing an increase in defecation frequency and reduced colonic transit time, thus supporting its role in digestive health.
https://research.monash.edu/en/publications/systematic-review-and-meta-analysis-the-effects-of-fermented-milk – This systematic review and meta-analysis assessed the effects of fermented milk containing *Bifidobacterium lactis*. Findings indicated improved gastrointestinal discomfort along with enhanced defecation frequency, supporting its inclusion in dietary products aimed at gut health.