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Bee propolis 70% extract

Also known as: Propolis, bee glue, bee propolis, Bee Propolis

Overview

Bee propolis is a resinous mixture collected by honeybees from tree buds, sap flows, or other botanical sources. Used by bees to seal and protect their hives, it is composed of a complex mixture of compounds, including flavonoids, phenolic acids, and terpenes, contributing to its antimicrobial, anti-inflammatory, and antioxidant properties. Propolis is available in various forms, including capsules, tinctures, and topical applications. It has been used in traditional medicine for centuries and continues to be explored for its potential health benefits. Research suggests propolis may support immune function, promote wound healing, and offer antioxidant protection. However, the quality of evidence varies, and more high-quality human studies are needed to confirm these effects.

Benefits

Propolis has demonstrated potential benefits in several areas. Research indicates it may improve immunity and lower blood pressure, though these findings are often based on small-scale studies. Its antioxidant and anti-inflammatory effects are well-documented, potentially contributing to cardiometabolic health benefits. Some studies suggest benefits for individuals with allergies or skin conditions. A literature review of 63 publications suggests propolis shows promise as an antioxidant and anti-inflammatory agent, particularly for cardiometabolic health, though most studies were cell-based or animal studies. A systematic review indicated mixed results for external use, with some benefits for skin and genital diseases but inconclusive due to methodological limitations.

How it works

Propolis exerts its effects through multiple biological pathways. Its antioxidant properties help neutralize free radicals, reducing oxidative stress. Anti-inflammatory actions modulate the immune response, potentially reducing inflammation. Flavonoids and phenolic acids in propolis may target various enzymes and receptors involved in inflammation and oxidation. While the exact mechanisms are still being investigated, propolis appears to interact with the immune system and may influence cardiovascular health. Limited data exists on human bioavailability, but animal studies suggest some absorption of its active compounds.

Side effects

Propolis is generally considered safe when used appropriately, but it can cause side effects in some individuals. Allergic reactions are the most common concern, particularly in those with bee allergies. Symptoms can range from mild skin irritation to severe anaphylaxis. Gastrointestinal upset is another potential side effect, although less common. Due to its potential antiplatelet effects, propolis may interact with blood thinners, increasing the risk of bleeding. It is contraindicated for individuals with known severe bee allergies. Pregnant or breastfeeding women should consult healthcare providers before using propolis. Always perform a patch test before topical use to check for allergic reactions.

Dosage

Recommended dosages of propolis vary depending on the form and intended use. Typically, oral dosages range from 500 to 1000 mg per day of propolis extract. However, there is no well-established minimum effective dose or maximum safe dose. Propolis is available in capsules, tinctures, and topical forms, and bioavailability may vary based on the formulation. There are no specific timing recommendations or required cofactors for propolis supplementation. Due to the risk of allergic reactions, it is advisable to start with a low dose and gradually increase as tolerated.

FAQs

Who should avoid taking propolis?

Individuals with known allergies to bees or bee products should avoid propolis due to the risk of allergic reactions. Pregnant or breastfeeding women should consult their healthcare provider before use.

How should I test for an allergic reaction before using propolis?

Apply a small amount of propolis to a discrete area of skin (like the forearm). Wait 24-48 hours. If redness, itching, swelling, or other signs of irritation occur, discontinue use and avoid propolis in the future.

Can propolis be taken with other medications?

Propolis may interact with blood-thinning medications due to its potential antiplatelet effects. Consult with a healthcare provider before taking propolis if you are on any medications, especially blood thinners.

What are the expected benefits of taking propolis?

Propolis is often used for its antioxidant and anti-inflammatory properties, and some studies suggest it may support immune function and promote wound healing. However, individual results may vary, and it is not a cure-all.

Research Sources

  • https://www.mdpi.com/2075-1729/15/5/764 – This systematic review and meta-analysis evaluated the external use of propolis for oral, skin, and genital diseases, including twelve studies. The review found mixed results, with some benefits for skin and genital diseases but noted that the findings were inconclusive due to methodological limitations and small sample sizes, indicating a moderate quality of evidence.
  • https://onlinelibrary.wiley.com/doi/10.1155/2017/8025752 – This literature review synthesized 63 publications and found that propolis shows promise as an antioxidant and anti-inflammatory agent, particularly for cardiometabolic health. The review noted that most studies were cell-based and animal studies, highlighting the need for more human trials to confirm these benefits.
  • https://www.tandfonline.com/doi/full/10.1080/00218839.2025.2498192?src= – This systematic review and meta-analysis focused on the antioxidant capacities of propolis. The review indicated that propolis exhibits significant antioxidant capacities, suggesting its potential role in reducing oxidative stress. Specific details regarding sample size and population were not available in the provided search results.
  • https://pubmed.ncbi.nlm.nih.gov/31717277/ – This study investigates the effects of propolis on blood pressure and vascular function. The research suggests that propolis supplementation may have a positive impact on cardiovascular health by improving blood pressure and vascular function, although further research is needed to confirm these findings.
  • https://nopren.ucsf.edu/sites/g/files/tkssra5936/f/wysiwyg/ONLY_newarticles_11Feb2022_Food.xlsx – This excel sheet contains a list of articles related to food and nutrition. While the specific details of propolis-related research within the sheet are not provided, it serves as a resource for potential studies on the health benefits of propolis.