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Ancient Liver Blend

Also known as: Ancient Liver Blend, Freeze-dried liver, Liver concentrate blends, Bovine liver powder, Ovine liver powder, Desiccated Liver

Overview

Ancient Liver Blend is a nutritional supplement typically composed of desiccated or freeze-dried animal liver, often bovine or ovine, combined with other liver-supportive herbs or nutrients. It is a nutrient-dense organ meat rich in vitamins (A, B12, folate), minerals (iron, copper), and other bioactive compounds. Marketed for liver health support, detoxification, improved energy, and nutrient replenishment, it is often used by individuals seeking natural sources of micronutrients or aiming to support hepatic function. The blend's composition can vary widely by manufacturer. While direct clinical research on 'Ancient Liver Blend' as a proprietary formula is limited, evidence supports the benefits of its individual components, such as desiccated liver and herbal liver-support supplements. These components are known for their high bioavailability of micronutrients, particularly vitamin A, B vitamins, and heme iron.

Benefits

Animal liver is a rich source of bioavailable vitamin B12 and iron, which can improve anemia and energy metabolism in deficient populations. Some herbs used in liver blends, such as curcumin and berberine, have been studied for liver enzyme improvement and reduction of liver fat in conditions like nonalcoholic fatty liver disease (NAFLD). Studies show reductions in ALT and AST levels by approximately 20-30% over 8-16 weeks in RCTs. Potential antioxidant and anti-inflammatory effects may also be present due to liver nutrients and herbal components. Individuals with nutritional deficiencies (e.g., iron-deficiency anemia, B12 deficiency) or mild liver dysfunction may experience the most benefit. Meta-analyses of herbal supplements show moderate improvements in liver enzymes and lipid profiles, with mean differences in ALT reductions around 10-15 U/L. Effects on liver markers are typically observed within 8-16 weeks.

How it works

Ancient Liver Blend works through multiple mechanisms. Nutrient replenishment, particularly with vitamin A, B12, and iron, supports erythropoiesis and cellular metabolism. Herbal components may modulate inflammatory pathways, oxidative stress, and lipid metabolism in hepatocytes. The primary interaction is with hepatic metabolism and systemic nutrient status. Known molecular targets include antioxidant enzymes, inflammatory cytokines, and mitochondrial function, especially for herbal components. Animal liver nutrients are highly bioavailable, while the bioavailability of herbal components varies depending on the formulation and co-factors.

Side effects

Ancient Liver Blend is generally safe when consumed in moderate amounts, but caution is warranted due to the potential for vitamin A toxicity and herb-induced liver injury (HILI) risks. Common side effects are rare but may include gastrointestinal discomfort. Uncommon side effects (1-5%) include allergic reactions and mild nausea. Rare side effects (<1%) include herb-induced liver injury reported with some herbal components (e.g., kava, Tusanqi), but not with desiccated liver itself. Potential drug interactions include anticoagulants (due to vitamin K content), retinoids, and hepatotoxic drugs. It is contraindicated in pregnancy (due to high vitamin A) and pre-existing liver disease without medical supervision. Pregnant women, individuals with liver disease, or vitamin A sensitivity should exercise caution.

Dosage

There is no established minimum effective dose for Ancient Liver Blend. Typical desiccated liver supplements provide 100-300 mg per serving. Optimal dosage varies by product; nutrient content should not exceed recommended daily allowances to avoid toxicity. Avoid exceeding upper intake levels for vitamin A (3000 mcg RAE/day for adults). It is best taken with meals to enhance absorption. Use capsules or powders standardized for nutrient content. Fat-soluble vitamins require dietary fat for optimal absorption. Adequate dietary fat and hydration are required cofactors.

FAQs

Is Ancient Liver Blend safe for everyone?

Generally safe for healthy adults, but caution is advised for pregnant women and those with liver conditions. Consult a healthcare provider before use.

How soon can benefits be expected?

Nutritional benefits may be noticed within weeks; liver function improvements may take 2-3 months with consistent use.

Can it replace liver-supporting medications?

No; it is a supplement, not a treatment. Consult with a healthcare provider for appropriate medical treatments.

Is it better than isolated vitamins?

Provides a complex nutrient matrix, potentially enhancing absorption and synergy compared to isolated vitamins. However, individual needs vary.

Research Sources

  • https://journals.lww.com/ajg/fulltext/9900/liver_cleansing_imposters__an_analysis_of_popular.1664.aspx – This article analyzes popular 'liver cleanse' products and highlights the lack of scientific evidence supporting their efficacy. It serves as a cautionary note regarding unsubstantiated claims in liver health supplements.
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC8281430/ – This systematic review on herb-induced liver injury (HILI) highlights that some herbs commonly used in liver supplements can cause liver damage, with mortality rates up to 27.7% in severe cases (e.g., Tusanqi). It underscores the need for caution and quality control in herbal blends.
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC10809338/ – This study by Mei et al. (2009) and Yan et al. (2015) conducted RCTs on herbal compounds (berberine) in NAFLD patients (n=47-184), showing significant reductions in ALT and hepatic fat content (p=0.008). This indicates potential liver benefits from herbal components sometimes included in blends, although limitations include open-label design in some studies.
  • https://onlinelibrary.wiley.com/doi/10.1155/2019/1484598 – This systematic review and meta-analysis on probiotics in NAFLD (Lin et al., 2019) found probiotics superior to placebo in improving liver enzymes and steatosis. This suggests that functional food components can modulate liver health, although not directly related to liver blends.
  • https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2023.1014010/full – This study by Rahmani et al. (2016) performed a double-blind, placebo-controlled RCT with curcumin (n=80) over 8 weeks, demonstrating a 78.9% improvement in liver fat and significant decreases in ALT, AST, and BMI compared to placebo. This supports the efficacy of certain herbal ingredients in liver blends.

Supplements Containing Ancient Liver Blend

Grass-Fed Liver by Ancient Nutrition
82

Grass-Fed Liver

Ancient Nutrition

Score: 82/100
GRASS-FED LIVER by Ancient Nutrition
73

GRASS-FED LIVER

Ancient Nutrition

Score: 73/100

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