Albion Zinc Bisglycinate Chelate
Also known as: Zinc Bisglycinate, Zinc Glycinate Chelate, Zinc Bisglycinate Chelate
Overview
Zinc Bisglycinate Chelate is a synthetic zinc compound where zinc is bound to two glycine molecules, greatly enhancing its bioavailability compared to other forms of zinc. Zinc is an essential mineral critical for various bodily functions and is naturally found in foods such as oysters, beef, and chicken. This compound is primarily utilized as a dietary supplement to promote immune health, wound healing, and protein synthesis. The chelation process protects zinc from inhibitors found in the stomach and intestines, allowing for better absorption. The level of research around Zinc Bisglycinate is moderate with good quality evidence supporting its use over other zinc forms for improving absorption and supporting various health outcomes.
Benefits
Zinc Bisglycinate is known for various evidence-backed benefits. It can significantly reduce inflammation markers like CRP and bolster CD4 levels, enhancing immune functions. Studies suggest that this form of zinc is about 43.4% more bioavailable than zinc gluconate, making it particularly beneficial for individuals suffering from zinc deficiency or at risk due to diets low in animal products or certain gastrointestinal conditions. Beyond immune support, zinc contributes to protein synthesis and wound healing, with clinical effects typically noticeable within weeks of supplementation. The body of research indicates that zinc supplementation favors improved health outcomes, particularly for the immune system.
How it works
Zinc plays a vital role in the immune system, DNA synthesis, and various enzymatic processes. It interacts with key molecular targets, including zinc finger proteins and enzymes like carbonic anhydrase, facilitating immune functions. By binding to glycine, Zinc Bisglycinate enhances its absorption, mitigating the inhibitory effects of dietary components encountered during digestion. This combination ensures that maximum amounts of zinc reach systemic circulation, where it can exert its physiological effects.
Side effects
Zinc Bisglycinate is generally considered safe when consumed within recommended doses. Common side effects include gastrointestinal upset, nausea, and diarrhea, particularly at high intake levels. More serious, but uncommon, reactions may include allergic responses or interactions that inhibit the efficacy of certain medications like antibiotics. Rarely, excessive zinc consumption can lead to toxicity, presenting symptoms such as vomiting or abdominal pain. Individuals with existing kidney or liver conditions should avoid high doses of zinc, and pregnant women along with those with compromised immune systems are advised to consult healthcare professionals before supplementation. It is essential to monitor for potential drug interactions, particularly with antibiotics, to maintain efficacy.
Dosage
The recommended dosage of Zinc Bisglycinate typically starts at around 15 mg of elemental zinc per day, with an optimal range of 15-30 mg daily for general health maintenance. The upper limit for adults is 40 mg per day. For best absorption and to minimize gastrointestinal discomfort, it's suggested to take zinc with meals. As absorption can be improved when taken with protein-rich foods, this should be considered when planning supplementation. While no specific cofactors are required, Vitamin C has been noted to potentially enhance zinc absorption.
FAQs
When should I take Zinc Bisglycinate?
It’s best taken with meals to minimize gastrointestinal side effects.
Are there any safety issues with Zinc Bisglycinate?
High doses can lead to toxicity. Consult a healthcare provider if unsure about dosage.
How soon can I expect results?
Improvements in immune function or wound healing may be noticeable within weeks of starting supplementation.
Is Zinc Bisglycinate a cure for immune issues?
No, it supports overall immune health but should be taken in conjunction with a balanced diet and other health practices.
Can I take this if I'm pregnant?
Consult with a healthcare provider before taking zinc supplements during pregnancy.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/33356467/ – This systematic review and meta-analysis included 35 RCTs with 1995 participants, findings indicated that zinc supplementation significantly reduced CRP and increased CD4 levels, highlighting the key immune benefits of zinc.
- https://dsld.od.nih.gov/ingredient/Zinc+Bisglycinate+Chelate – A comprehensive review examining various forms of zinc, including Zinc Bisglycinate, noted its improved absorption metrics compared to other forms.
- https://www.mdpi.com/2072-6643/16/24/4269 – The paper analyzes the absorption and bioavailability of zinc forms, confirming that zinc glycinate and gluconate are among the most readily absorbed variants.
Supplements Containing Albion Zinc Bisglycinate Chelate
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