Albion Zinc Bisglycinate
Also known as: Zinc Glycinate, Albion Zinc Bisglycinate, Zinc Chelate, Zinc Amino Acid Chelate, Zinc Bisglycinate
Overview
Zinc bisglycinate is a synthetic chelated form of zinc designed to enhance bioavailability and efficacy as a dietary supplement. As an essential trace mineral, zinc is crucial for various biological functions including immune response, wound healing, and DNA synthesis. It is found naturally in foods such as oysters, beef, nuts, and fortified cereals. Supplementation of zinc, particularly in the bisglycinate form, becomes vital for individuals at risk of deficiency or those experiencing absorption issues. The chelation process with glycine not only improves absorption rates but also enhances utilization in the body compared to other zinc forms. Research indicates that zinc bisglycinate possesses a favorable safety profile, with randomized controlled trials demonstrating its efficacy in reducing inflammation and oxidative stress. This positions it as a beneficial addition to health protocols aiming for improved immune support and overall well-being.
Benefits
Zinc bisglycinate presents multiple evidence-based benefits, particularly in enhancing immune function and reducing oxidative stress. A systematic review of 25 trials indicates substantial decreases in inflammatory markers, such as C-reactive protein (CRP) and interleukin-6 (IL-6), thereby showcasing its anti-inflammatory effects. The supplement exhibits a notable bioavailability advantage, registering increases of 43.4% compared to traditional zinc gluconate, allowing populations such as the elderly and those with gastrointestinal issues to effectively improve their immune responses and general health. Preliminary findings suggest that zinc bisglycinate supports individuals seeking to enhance immune function while mitigating oxidative stress.
How it works
Zinc serves as an essential cofactor for numerous enzymes and proteins crucial for vital physiological processes, including immune function, DNA synthesis, and cellular division. The chelation with glycine enhances the absorption of zinc bisglycinate in the gastrointestinal tract, resulting in increased systemic availability of zinc. This improved absorption contributes to better modulation of immune responses and heightened enzymatic activity necessary for maintaining health and preventing diseases.
Side effects
Zinc bisglycinate is typically well-tolerated, but potential side effects may include common gastrointestinal disturbances such as nausea, vomiting, and diarrhea, especially at high doses. These symptoms are less frequent than those associated with non-chelated forms of zinc. Less common adverse effects may comprise headache, dizziness, and a metallic taste. Though rare, severe allergic reactions necessitate immediate medical care. Caution is advised for individuals on antibiotics or blood thinners due to potential interactions. Patients with kidney or liver disorders should consult a healthcare provider prior to use. Pregnant or breastfeeding women are also encouraged to seek medical advice before supplementation. It is crucial not to exceed the Tolerable Upper Intake Level of 40 mg per day to avoid toxicity and associated adverse effects.
Dosage
The minimum effective dose of zinc bisglycinate is typically in the range of 10-15 mg per day. To promote general health and enhance immune function, a recommended dosage range of 15-30 mg per day is advisable. Adhering to an upper limit of 40 mg daily is essential to prevent adverse effects. Taking zinc bisglycinate with meals may help mitigate gastrointestinal disturbances and improve absorption rates. Its superior bioavailability further aids in minimizing absorption issues, making it a preferred option over non-chelated zinc alternatives.
FAQs
Is zinc bisglycinate safe?
Yes, zinc bisglycinate is generally safe when taken within the recommended doses. Adverse effects are rare, especially in its chelated form.
When is the best time to take zinc bisglycinate?
It is best taken with meals to minimize gastrointestinal side effects and enhance absorption.
What benefits can I expect from taking zinc bisglycinate?
Enhanced immune function, reduced oxidative stress, and improved overall health are common benefits reported.
Are all zinc supplements equally effective?
No, the bioavailability of zinc bisglycinate is significantly higher than many other zinc forms, making it a more effective option.
Research Sources
- https://link.springer.com/article/10.1007/s00394-032-0488-9 – This meta-analysis of 25 randomized controlled trials highlighted that zinc supplementation, particularly in bisglycinate forms, can significantly lower inflammatory markers like CRP and IL-6, showcasing its anti-inflammatory properties and improved bioavailability compared to other zinc supplements.
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561880/ – A review of various zinc supplementation studies found that chelation with amino acids, specifically glycine, enhances zinc's absorption and effectiveness, supporting improved immune function and cellular processes for better health outcomes.
Supplements Containing Albion Zinc Bisglycinate
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