Agaricus Bisporus Fruit Extract
Also known as: button mushroom, white mushroom, champignon, Agaricus bisporus fruit extract, Agaricus bisporus
Overview
Agaricus bisporus is a widely consumed edible mushroom known for its culinary versatility and numerous health benefits. It is rich in bioactive compounds, including polysaccharides (notably β-glucans), proteins, phenolics, and antioxidants. Commonly available in fresh, canned, or dried forms, this mushroom is featured in a variety of cuisines. Numerous studies, primarily in animal models and some human trials, suggest that Agaricus bisporus exhibits anti-obesity, antioxidant, anti-diabetic, and anti-inflammatory effects. These properties are attributed to its rich nutrient profile and have garnered considerable interest in the context of dietary supplements, establishing it as a well-researched ingredient.
Benefits
Research indicates several benefits linked to Agaricus bisporus extract (ABE). The most notable effect is its anti-obesity potential, where ABE has demonstrated a reduction in body weight gain and fat accumulation in obese mice through the inhibition of pancreatic lipase and enhancement of lipid metabolism. Furthermore, its antioxidant properties help mitigate oxidative stress related to various chronic conditions. Studies also suggest potential anti-diabetic effects, with ABE showing improvements in lipid profiles and glucose levels in both animal and human studies, particularly among overweight individuals. While the strength of evidence is moderate to advanced, further well-controlled human studies are necessary for conclusive benefits.
How it works
Agaricus bisporus extract primarily functions by inhibiting pancreatic lipase, a critical enzyme in fat digestion, thereby reducing fat absorption in the intestines. This mechanism also involves the downregulation of PPAR γ (peroxisome proliferator-activated receptor gamma), which is crucial in regulating fat cell differentiation and metabolism. Additionally, ABE may induce autophagy, promoting cellular maintenance that supports improved metabolic health through enhanced lipid and glucose metabolism.
Side effects
Generally considered safe, the predominant side effect of Agaricus bisporus extract is gastrointestinal discomfort, attributed to its high fiber content; however, this has been noted infrequently. Given the lack of extensive long-term studies on human populations, caution is urged when introducing this supplement into one’s diet. Rare allergic reactions have been reported in sensitized individuals. While no well-documented drug interactions exist, caution should be used with medications that affect lipid metabolism. Pregnant or breastfeeding women and individuals with mushroom allergies should seek medical advice prior to use.
Dosage
Recommended dosages for Agaricus bisporus extract vary but are commonly seen in the range of 100 mg to 500 mg daily. For optimal therapeutic effects, doses of 200-300 mg per day of the water-soluble polysaccharide form are supported by research. Although no specific upper safety limit has been established, doses up to 500 mg per day have been tolerated well without significant adverse effects. Timing of consumption is flexible; however, taking it with meals may enhance absorption. Additional investigation into bioavailability and efficacy related to specific forms of the extract is warranted.
FAQs
Is Agaricus bisporus extract safe for long-term use?
While Agaricus bisporus extract is generally safe, the long-term effects have not been extensively studied.
When is the best time to take this supplement?
You can take it with meals, although specific timing is not critical for effectiveness.
What results can I expect?
Users may see potential weight loss and improvements in lipid profiles over the course of several weeks.
Is this extract a quick solution for obesity?
No, it should be used as part of a comprehensive approach to weight management.