Agaricus Bisporus Extract
Also known as: Button mushroom, White button mushroom, Brown button mushroom, Agaricus bisporus
Overview
*Agaricus bisporus* is one of the most widely consumed mushroom species worldwide, found naturally in fields and meadows, and extensively cultivated. It not only serves as a popular food ingredient but is also recognized for its potential health benefits, making it a valuable supplement. The extracts of *Agaricus bisporus* contain bioactive compounds such as polysaccharides (like beta-glucans), phenolic acids, and vitamins that contribute to its properties. Research has indicated that these extracts may possess antioxidant, anti-inflammatory, anti-obesity, and immune-modulating effects. While there are numerous in vitro and animal studies, the research is considered moderately mature, indicating a need for more robust human trials to validate its efficacy and establish safety parameters.
Benefits
The primary benefits of *Agaricus bisporus* extract include: 1. **Anti-obesity Effect**: Research demonstrates a 20-30% reduction in body weight gain in mice fed a high-fat diet following treatment, indicating notable weight loss benefits. 2. **Antioxidant and Anti-inflammatory Activities**: Ethanolic extracts effectively scavenge free radicals and reduce inflammation, showing promise for chronic disease prevention. 3. **Immune Modulation**: Beta-glucans in the extract can stimulate immune function, enhancing overall immunity. 4. **Cancer Prevention**: Preliminary studies suggest a protective action against certain cancers, notably breast cancer. Users targeting metabolic health, particularly those managing obesity or inflammation, may experience the most benefits. However, comprehensive studies in humans are still required for conclusive evidence.
How it works
The extract operates primarily through inhibition of pancreatic lipase, which reduces fat absorption in the gastrointestinal system. Additionally, polysaccharides stimulate the immune system, enhancing immune response. Antioxidant properties are exerted by scavenging reactive oxygen species, while anti-inflammatory actions occur through modulation of macrophage activity. Together, these mechanisms contribute to the overall health benefits associated with *Agaricus bisporus*.
Side effects
Overall, *Agaricus bisporus* extract is considered safe for consumption when taken in moderation. Common side effects (>5%) are not reported; however, some individuals may experience uncommon side effects (1-5%), such as allergic reactions or gastrointestinal discomfort. Rare side effects (<1%) are not indicated in the current literature. Caution is advised for individuals on medications affecting the immune system or metabolic pathways due to potential interactions. Those with mushroom allergies should avoid this extract, and pregnant or breastfeeding women should consult a healthcare provider prior to use to ensure safety.
Dosage
The effective dosage range varies depending on the health goal. Animal studies suggest an effective range of 100-500 mg/kg body weight per day for anti-obesity effects. In limited human studies, doses between 500-1000 mg per day have provided positive outcomes. There is no established maximum safe dose, but exceeding 1000 mg may not have sufficient research to support its safety. To optimize absorption, it is recommended that the extract be taken with meals. The method of extraction can also impact bioavailability, with polysaccharide-rich extracts typically being more effective when solubility is ensured. No specific cofactors are necessary, although adequate hydration and nutrition can support the efficacy of the compounds.
FAQs
Is *Agaricus bisporus* extract safe?
Yes, it is generally safe for most people, but consult a healthcare provider if you have allergies or take medications affecting your immune system.
When should I take *Agaricus bisporus* extract?
There are no specific timing recommendations, but taking it with meals is thought to enhance absorption.
What results can I expect from this supplement?
Potential outcomes include weight loss, improved metabolism, and enhanced immune function, based on animal and limited human studies.
Can I rely on this extract for weight loss?
While it may support weight loss, it should complement a balanced diet and lifestyle rather than serve as a sole solution.
Research Sources
- https://www.mdpi.com/2304-8158/13/11/1715 – This systematic review discusses the health effects of *Agaricus bisporus*, highlighting its impact on metabolic syndrome, immune function, and cancer prevention. Strong evidence supports its role in Vitamin D status enhancement.
- https://pubmed.ncbi.nlm.nih.gov/33352884/ – The study details the anti-obesity effects of *Agaricus bisporus* extract in a mouse model, showcasing significant reductions in body weight and fat deposition relative to control.
- https://www.mdpi.com/2072-6643/15/19/4225 – This article presents findings on the anti-inflammatory and antioxidant properties of ethanolic extracts from *Agaricus bisporus*, suggesting potential therapeutic applications.
- https://pubmed.ncbi.nlm.nih.gov/32653808/ – The study explores the immune-modulating effects of *Agaricus bisporus* extracts, particularly focusing on the role of polysaccharides in enhancing immune responses.
- https://onlinelibrary.wiley.com/doi/abs/10.1111/jfbc.13979 – This investigation reviews the bioactive compounds in mushrooms, specifically *Agaricus bisporus*, discussing their potential health benefits including antioxidant and anti-inflammatory properties.
