African Mango Seed Extract
Also known as: African mango, African mango seed extract, Wild mango, Bush mango, Irvingia gabonensis
Overview
African Mango Seed Extract is derived from the seeds of the Irvingia gabonensis tree, native to Central and West Africa. Traditionally valued for its nutritional and medicinal properties, this extract is predominantly marketed as a weight loss supplement. It is characterized by its rich content of fiber, protein, and healthy fats, alongside various bioactive compounds like flavonoids, alkaloids, and saponins. Research on this extract's efficacy is at a moderate level, with a mix of promising clinical trials and variable overall evidence quality. Many studies illustrate potential weight loss benefits and improvements in metabolic health, although methodological limitations in some studies warrant cautious interpretation of results.
Benefits
The most notable evidence-based benefits of African Mango Seed Extract include significant weight loss and improvements in lipid profiles. A systematic review indicated an average weight loss of approximately 3.2 kg compared to placebo (p < 0.001). Additionally, a randomized controlled trial showed a reduction in total cholesterol by 26.2%, LDL cholesterol by 27.3%, and triglycerides by 14.6% over ten weeks (p < 0.05). The extract may also assist in blood sugar regulation, although evidence on this is less conclusive. Research overwhelmingly focuses on obese populations, who appear to experience the most pronounced benefits from supplementation.
How it works
African Mango Seed Extract operates through several biological mechanisms, including the inhibition of adipogenesis, which is the formation of fat cells, and the enhancement of fat oxidation. It also influences hormonal regulation by modulating levels of leptin and adiponectin, vital for appetite control and metabolism. The active compounds target the PPARγ (peroxisome proliferator-activated receptor gamma), a crucial regulator of fat cell functionality, and may enhance insulin sensitivity. Absorption and bioavailability of these compounds are likely supported by gastrointestinal processes.
Side effects
African Mango Seed Extract is generally viewed as safe when taken in recommended dosages. Common side effects, occurring in more than 5% of users, include gastrointestinal symptoms such as nausea, diarrhea, and flatulence. Less frequent effects (1-5%) may involve headaches and dizziness, with no significant rare side effects reported. Users on diabetes or cholesterol medications should exercise caution, as the extract may interact with these drugs. Pregnant or breastfeeding women, as well as those with severe gastrointestinal disorders, should avoid its use. It is critical to consult with healthcare providers before starting supplementation, especially for individuals with underlying medical concerns.
Dosage
The commonly recommended dosage of African Mango Seed Extract ranges from 150 mg to 350 mg per day, aligning with most clinical studies. A suggested minimum effective dose is between 150-300 mg daily, though a definitive maximum safe limit is not established, and doses exceeding 350 mg have not been extensively studied. For increased satiety and fat oxidation, taking the extract before meals is recommended. The supplement is typically available in capsules or tablets, and consumption with healthy fats may enhance absorption. Users are advised to maintain a balanced diet and regular physical activity to optimize desired outcomes.
FAQs
How Long Does It Take to See Results?
Benefits are typically observed within 4-10 weeks of consistent supplementation.
Is It Safe for Everyone?
Generally safe, but caution is advised for pregnant women and individuals with severe gastrointestinal disorders.
Can It Be Used with Other Supplements?
Yes, it can be combined with other supplements, but monitor for possible interactions with diabetes and cholesterol medications.
What Are the Expected Results?
Significant weight loss and improvements in lipid profiles are commonly reported outcomes.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/22968611/ – This systematic review analyzed multiple studies on African Mango Seed Extract and its effects on weight loss and metabolic health. Results indicated significant reductions in body weight and improved lipid profiles for participants, reinforcing its potential as an effective supplement for obese individuals.
- https://pubmed.ncbi.nlm.nih.gov/20103313/ – The randomized controlled trial highlighted in this research demonstrated that supplementation with African Mango Seed Extract led to substantial decreases in cholesterol levels, showcasing its efficacy in promoting lipid health over a ten-week period.
Supplements Containing African Mango Seed Extract
Formula One All Natural Diet Drops With African Mango
EFL Nutritionals
Coffee Ketone Mango Combo
Bio Nutrition
Premium Cleanse Pure Extract
Pure Supplements
Standardized African Mango
Nature's Way
African Mango Alcohol Free
Hawaii Pharm
African Mango
Hawaii Pharm