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Schisandra Chinensis Extract

Also known as: Chinese Magnolia Vine, Five-Flavor Berry, Schisandra, Wu Wei Zi, Schisandra chinensis

Overview

*Schisandra chinensis* is a medicinal plant native to East Asia, commonly utilized in traditional Chinese medicine for its various health benefits. This herb contains bioactive compounds such as lignans (notably Schisandrin A), flavonoids, and vitamins, making it a rich source of antioxidants. Its primary applications involve enhancing immune function, acting as an antioxidant, reducing inflammation, and potentially improving cognitive functions and physical performance. While its health-promoting effects are supported by some studies, the research is still developing, necessitating further rigorous investigations to fully establish its efficacy and safety in human populations.

Benefits

Numerous studies highlight *Schisandra chinensis* as beneficial for various health aspects. One significant finding indicates that it can improve muscle strength and lower lactate levels in post-menopausal women, with a notable *p* value of < 0.001 in muscle strength enhancement after 12 weeks of use. Its antioxidant capabilities may also bolster cognitive functions, offering potential improvements to memory and learning. Furthermore, the extract exhibits anti-inflammatory properties and might boost immunity, although human studies to confirm these effects are sparse. These benefits collectively imply that post-menopausal women, athletes, and those seeking cognitive support may gain the most from supplementation.

How it works

The active components within *Schisandra chinensis*, primarily lignans like Schisandrin A, exert their effects through antioxidant pathways, modulating cellular stress responses and inflammatory processes. The extract has been shown to influence NF-κB signaling, enhancing immune responses and reducing oxidative damage. Furthermore, its potential effects on cognitive functions are believed to occur via improved blood circulation and antioxidant activity in the nervous system, helping to mitigate neurodegenerative processes.

Side effects

*Schisandra chinensis* is generally considered safe for most individuals; however, comprehensive safety data is limited. Commonly reported side effects may include gastrointestinal disturbances, such as diarrhea and abdominal discomfort, while allergic reactions are less frequently observed. There are concerns regarding interactions with medications such as blood thinners and antidiabetic medications due to its potential antioxidant properties. Pregnant and breastfeeding individuals are advised against its use due to inadequate safety studies. Caution is recommended for those with severe allergies or who are concurrently taking multiple medications, as interactions with herbal supplements may occur.

Dosage

The recommended dosage of *Schisandra chinensis* typically ranges from 500 to 1000 mg per day, with studies indicating positive outcomes at around 1000 mg daily. While minimum effective doses are not well-established, utilizing higher doses should be approached with caution due to the absence of defined maximum safe limits. Maintaining consistent daily intake without specific timing recommendations may lead to better outcomes. The bioavailability of the active compounds can vary based on the extraction methods and individual's metabolism; thus, using standardized extracts (such as capsules) is advisable for reliable dosing.

FAQs

What should I consider before starting *Schisandra chinensis*?

It's important to start with a low dose and monitor for any side effects. Consult a healthcare provider if you are on medications or have health concerns.

How safe is *Schisandra chinensis*?

Generally regarded as safe, but comprehensive safety data is limited, especially during pregnancy or breastfeeding. Monitor for any adverse effects.

What results can I expect and when?

Benefits such as enhanced muscle strength or cognitive improvement may take several weeks to manifest, varying by individual response.

Can *Schisandra chinensis* replace medical treatments?

No, it should not be viewed as a substitute for medical treatment, and it's crucial to consult healthcare providers prior to use.

Is there a preferred time to take it?

There are no specific timing recommendations, but consistent daily intake is generally advised for optimal benefits.

Research Sources

  • https://jtd.amegroups.org/article/view/35966/html – This study suggests that supplementation with *Schisandra chinensis* can significantly improve muscle strength and lower lactate levels in post-menopausal women over a 12-week period, although sample size limitations are noted.
  • https://pubmed.ncbi.nlm.nih.gov/37560060/ – Research highlights *Schisandrin A*, a key component of *Schisandra chinensis*, showing effective modulation of oxidative stress and anti-inflammatory responses in lung epithelial cells, indicating its protective properties.
  • https://www.mdpi.com/1660-4601/17/7/2475 – This study demonstrated that *Schisandra chinensis* could enhance cognitive function and learning in animal models, warranting further investigations in human populations for confirmation.
  • https://pubmed.ncbi.nlm.nih.gov/32260466/ – This publication reviews multiple studies on *Schisandra chinensis*, noting its various health benefits, but emphasizes the need for more rigorous human trials to validate its effectiveness.
  • https://journals.sagepub.com/doi/full/10.1177/1934578X20970855 – The article discusses the antioxidant and anti-inflammatory roles of *Schisandra chinensis*, outlining its potential health benefits while calling for further clinical research.

Supplements Containing Schisandra Chinensis Extract

Max ARM Watermelon by MM Sports Nutrition
75

Max ARM Watermelon

MM Sports Nutrition

Score: 75/100
Liverclean by Dr. Venessa's Formulas
50

Liverclean

Dr. Venessa's Formulas

Score: 50/100
Liver DS by MDLogic
80

Liver DS

MDLogic

Score: 80/100
An Shen Bu Xin Teapills by Plum Flower
65

An Shen Bu Xin Teapills

Plum Flower

Score: 65/100
Five Ancestors Teapills by Plum Flower
68

Five Ancestors Teapills

Plum Flower

Score: 68/100
Qi Guan Yan Pills by Plum Flower
73

Qi Guan Yan Pills

Plum Flower

Score: 73/100
Schisandra Chinensis 750 mg by SuperSmart
70

Schisandra Chinensis 750 mg

SuperSmart

Score: 70/100