Proprietary Blend Of
Also known as: Sphaeranthus indicus, East Indian globe thistle, Gorakhmundi, Mangifera indica, Mango tree, LI12542F6, Sphaeranthus indicus and Mangifera indica extract
Overview
This proprietary blend of *Sphaeranthus indicus* (East Indian globe thistle) flower head and *Mangifera indica* (mango tree) stem bark extracts is primarily utilized to enhance muscle strength, size, and endurance. The *Sphaeranthus indicus* plant is traditionally used in Ayurvedic medicine for various health benefits, while the bark of the mango tree has roots in traditional medicinal practices. Although the exact composition of this standardized blend is not publicly disclosed, it is marketed for its efficacy and safety as a botanical formulation. Research backing this blend includes a randomized controlled trial indicating significant improvements in muscle metrics after a 56-day supplementation period, though the evidence remains limited and specific to healthy young males.
Benefits
The proprietary blend has shown significant benefits, including improvements in muscle strength (bench press, leg press, handgrip strength), endurance (time to exhaustion), and body composition metrics. Statistical analysis indicated significant gains in all primary outcomes (P < 0.0001 for various strength measures; P < 0.0008 for endurance). Additionally, favorable changes in serum hormone levels, specifically free testosterone and cortisol, were noted. The study focused on healthy males aged 18-40, and results were consistent across participants, highlighting that this formulation may be particularly beneficial for athletic or physically active individuals. Notably, no adverse events were reported, suggesting good tolerability among participants.
How it works
The precise mechanisms of action for this proprietary blend are not fully defined; however, it is theorized that the extracts modulate hormone levels, particularly testosterone and cortisol, and enhance muscle protein synthesis. Interactions likely occur with various biological pathways associated with muscle growth, endurance, and recovery, via impacts on both the musculoskeletal and endocrine systems. Future research would benefit from identifying specific molecular targets and pathways involved.
Side effects
The proprietary blend has demonstrated a favorable safety profile, with no adverse effects recorded during the 56-day study. There were no common (>5%), uncommon (1-5%), or rare (<1%) side effects reported among participants, indicating high tolerability for the specific demographic studied. Furthermore, there is no available data on potential drug interactions or contraindications. Special populations, including pregnant women, children, or those with chronic health conditions, were not assessed in the study, resulting in an absence of safety information for these groups. Hence, while the blend appears safe for healthy young males, caution is advised regarding its use in broader populations until further evaluations are conducted.
Dosage
The study utilized a minimum effective dose of 650 mg/day for the proprietary blend. Although this dosage is rooted in the research conducted, optimal ranges beyond this amount have not been established. The specific timing for ingestion was not addressed in the study, indicating daily supplementation without particular timing recommendations. The blend was administered in capsule form, with no reported absorption factors or required cofactors mentioned. Importantly, upper limits for dosing remain undefined, necessitating further research on maximum safe doses.
FAQs
How should I take this supplement?
The supplement is best taken as directed, with no specific timing indicated. Daily administration is recommended.
Is this supplement safe?
The blend has shown good tolerability in the studied population with no adverse events; however, long-term safety is not yet established.
What results can I expect?
Users may anticipate improvements in muscle strength, endurance, and body composition after several weeks of consistent use.
Can I use this supplement if I have health conditions?
Caution is advised for individuals with chronic health conditions, as safety in special populations has not been evaluated.
Are there any interactions with medications?
No specific drug interactions have been identified; however, consult a healthcare professional before combining with other medications.
Research Sources
- https://foodandnutritionresearch.net/index.php/fnr/article/view/8972 – This randomized, double-blinded, placebo-controlled trial evaluated the efficacy of the proprietary blend on muscular strength and hormone levels in 40 healthy young males. The results were statistically significant across various strength measures and endurance tests, with no reported adverse effects, indicating a well-tolerated formulation.
- https://pubmed.ncbi.nlm.nih.gov/38219250/ – This study supports the findings of the primary research by highlighting the muscle-enhancing properties of *Sphaeranthus indicus* and *Mangifera indica*. It emphasizes the need for further investigation of the underlying mechanisms and broader efficacy across different populations.
- https://pubmed.ncbi.nlm.nih.gov/37004873/ – This article discusses the traditional uses of *Mangifera indica* in medicine, providing context on the historical application of the ingredient and drawing connections to potential modern health benefits.
- https://pubmed.ncbi.nlm.nih.gov/36502789/ – This systematic review examines the role of herbal supplements in muscle performance, offering insights that can be applied to understanding the mechanism of action of the proprietary blend.
Supplements Containing Proprietary Blend Of
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