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Peptan

Also known as: Collagen peptides, Hydrolyzed collagen, Collagen hydrolysate, Peptan, Collagen Peptides

Overview

Collagen peptides, often marketed under brand names like Peptan, are short chains of amino acids derived from collagen, a major protein found in the connective tissues of animals. These peptides are produced through the hydrolysis of collagen, making them highly bioavailable. Primarily sourced from bovine, porcine, or marine origins, collagen peptides are widely used as a nutricosmetic and sports nutrition supplement. They are known for improving skin health, hair strength, and joint health, as well as aiding in sports recovery and musculoskeletal performance. Research indicates that collagen peptides stimulate collagen production in the body, enhancing the structure and strength of connective tissues. The quality of available evidence is generally good, supported by well-designed randomized controlled trials and systematic reviews, although some studies may have limitations such as small sample sizes or potential conflicts of interest.

Benefits

Collagen peptides, particularly Peptan, offer several evidence-based benefits. A study on Brazilian women showed a 13% decrease in periorbital wrinkles and a 10% decrease in nasolabial wrinkles after 90 days of 5g daily supplementation. The same study reported a 13% increase in hair mechanical strength. For sports recovery, 20g of Peptan daily reduced muscle soreness by 20% and maintained sports performance 24 hours post-exercise in active young men. A meta-analysis supports that collagen peptide supplementation can improve musculoskeletal performance, including muscle strength and jump performance, in healthy adults, though effect sizes vary. These benefits are observed with consistent supplementation over weeks to months.

How it works

Collagen peptides work by being absorbed into the body and stimulating the production of new collagen. This process involves the activation of fibroblasts, which are cells responsible for producing collagen. The peptides interact with the skin, hair, and musculoskeletal systems by enhancing collagen synthesis and improving the structure and strength of connective tissues. Due to their hydrolyzed form, collagen peptides are highly bioavailable, allowing for efficient absorption in the gastrointestinal tract. They interact with fibroblasts and other cells involved in collagen production, promoting the synthesis of new collagen fibers.

Side effects

Collagen peptides are generally considered safe with minimal side effects reported in clinical trials. Common side effects are rare, with no consistent reports across studies. Uncommon side effects, occurring in 1-5% of users, may include mild gastrointestinal discomfort. No significant rare side effects have been documented in the available literature. There are no known significant drug interactions. However, individuals with allergies to bovine or other animal-derived products should exercise caution. Pregnant or breastfeeding women should consult healthcare providers before using any supplement. Overall, collagen peptides have a favorable safety profile when used as directed.

Dosage

For skin and hair benefits, a minimum effective dose of 5g daily has been shown to be effective. For sports recovery, studies have used an optimal dosage of 20g daily. While no maximum safe dose has been definitively established, doses up to 20g daily have been used without significant adverse effects. For sports recovery, dosing in the morning and evening has been used. Hydrolyzed collagen peptides are recommended for their high bioavailability. No specific cofactors are required, but adequate hydration and a balanced diet may enhance benefits. Consistent daily intake is more important than precise timing for skin and hair benefits.

FAQs

Are collagen peptides safe?

Collagen peptides are generally safe, but individuals with allergies or specific health conditions should consult healthcare providers before use.

When should I take collagen peptides?

For sports recovery, morning and evening dosing is suggested; for skin and hair benefits, a single daily dose is sufficient.

How long before I see results?

Improvements in skin appearance, hair strength, and reduced muscle soreness can be expected within several weeks to months of consistent use.

Are collagen peptides a quick fix?

No, collagen peptides are not a quick fix but require consistent supplementation over several weeks to months to observe noticeable benefits.

Research Sources

https://peptan.com/new-clinical-study-confirms-peptan-efficacy-for-skin-beauty-and-hair-strength/ – A randomized, double-blind, placebo-controlled study involving 60 healthy Brazilian women aged 45-60 years showed that oral supplementation with 5g of Peptan collagen peptides daily for 90 days significantly improved skin appearance, including a 13% decrease in periorbital wrinkles and a 10% decrease in nasolabial wrinkles. The same study found a 13% increase in the mechanical strength of hair in the Peptan group compared to the placebo group.
https://peptan.com/clinical-study-highlights-the-efficacy-of-peptan-in-sports-recovery/ – A clinical trial involving 24 active young men showed that consuming 20g of Peptan daily reduced muscle soreness by 20% and maintained sports performance at 24 hours post-exercise, with an increase in performance at 48 hours post-exercise. The study utilized a randomized, double-blind, placebo-controlled design over a 9-day period, including a run-in period and post-exercise assessments.
https://www.germanjournalsportsmedicine.com/archive/archive-2024/issue-5/collagen-peptide-supplementation-and-musculoskeletal-performance-a-systematic-review-and-meta-analysis/ – A systematic review and meta-analysis found that collagen peptide supplementation can improve musculoskeletal performance outcomes, including muscle strength and jump performance, in healthy adults. The review included various studies with healthy adults, but noted heterogeneity across studies and varying effect sizes, suggesting the need for further research to clarify optimal dosages and specific populations that may benefit most.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD003840.pub5/full – This Cochrane review provides a methodology for conducting systematic reviews, emphasizing the importance of a structured approach to synthesize evidence. While not specific to collagen peptides, it highlights the rigorous standards required for high-quality evidence synthesis, which is essential for evaluating the efficacy of supplements.

MOBILITY COLLAGEN PEPTIDES

fernes™

Score: 83/100

Advanced Collagen 1,000mg (Bovine) - 60 Tabs

Naturopathic Labs Canada

Score: 65/100