Goji Fruit Extract
Also known as: Goji berry, wolfberry, *Lycium barbarum* L.
Overview
Goji berries, scientifically known as *Lycium barbarum*, are native to East Asia, especially China, and have a rich history in traditional medicine. Recognized for their high content of bioactive compounds like polysaccharides, carotenoids, and flavonoids, they are primarily consumed dried, as juice, or in supplement form. They are mainly utilized for boosting immune function, enhancing antioxidant defenses, and promoting eye health. Current research indicates a moderate understanding of their effects, with ongoing studies focused on long-term benefits and optimal dosages, yet some high-quality randomized controlled trials (RCTs) are available. Key characteristics include notable antioxidant potential and immune-modulating effects, which are central to their health-promoting claims.
Benefits
Goji berries are associated with several evidence-based benefits. Primarily, research indicates their **immune modulation** effects, particularly in older adults, where studies have reported increased lymphocyte counts and interleukin-2 levels. Furthermore, they exhibit significant **antioxidant effects**, increasing markers such as superoxide dismutase and glutathione peroxidase. Secondary benefits include **mental health support**, with some evidence suggesting enhancements in sleep quality and cognitive function, and **cardiovascular health**, though studies yield mixed results regarding lipid regulation. The elderly population may reap the most significant benefits, exhibiting moderate effect sizes for both immune and antioxidant outcomes. Short-term benefits have been documented, yet longer-term effects necessitate further investigation.
How it works
The efficacy of goji berries is primarily attributed to their interaction with immune and antioxidant biological pathways. They modulate immune responses and enhance antioxidant defenses, countering oxidative stress and inflammation. The bioactive compounds, particularly polysaccharides and carotenoids, appear to target immune cells and antioxidant enzymes, although the specific mechanisms and absorption levels of these compounds require further elucidation.
Side effects
Goji berries are generally regarded as safe for consumption in traditional amounts, with no common adverse effects (>5%) consistently reported in clinical studies. Some individuals may experience uncommon side effects (1-5%) such as allergic reactions or gastrointestinal upset, particularly among those with sensitivities. Rare side effects (<1%) have not been well-documented. Caution is advised regarding potential interactions with blood thinners or diabetes medications due to their antioxidant properties. Pregnant and breastfeeding individuals should also exercise caution due to limited information on safety in these populations. Individuals with allergies or those taking interacting medications should be particularly careful when consuming goji berries.
Dosage
The optimal dosages for goji berries vary as specific recommendations are not well established. Traditional consumption involves dried berries and juice, with studies often utilizing standardized dosages of 120 mL of juice or 15 g of dried berries daily. Although an exact maximum safe dose is not defined, it is advisable to avoid excessively high doses that may increase interaction risks. No specific timing for intake is recommended; however, consistent daily consumption is suggested. Different forms of goji berries (dried, juice, extracts) may vary in bioavailability and absorption rates, which also necessitates consideration of individual factors.
FAQs
What should I look for when buying goji berry products?
Ensure they are sourced from reputable suppliers to minimize contamination risks, and check for standardized extracts for potency.
Are goji berries safe to take with medications?
Generally safe, but monitor for potential interactions with blood thinners or diabetes medications.
How should I take goji berries?
Consistent daily intake is encouraged, whether through dried berries, juice, or supplements.
When can I expect to see benefits from goji berries?
Enhanced immune function and antioxidant defenses may be noticeable within weeks of regular intake.
Are goji berries a miracle cure?
No, goji berries offer supportive health benefits but are not a cure-all. Their benefits are generally supportive rather than therapeutic.
Research Sources
- https://journals.lww.com/md-journal/fulltext/2021/12100/efficacy_of_lycium_barbarum_l__on_plasma_lipid.73.aspx – This systematic review highlights the need for further rigorous studies on the effects of *Lycium barbarum* on plasma lipid levels, reflecting the potential cardiovascular benefits but underscoring the current variability in evidence quality.
- https://pubmed.ncbi.nlm.nih.gov/30728882/ – A randomized controlled trial by Toh et al. demonstrated that regular consumption of dried *L. barbarum* significantly boosted plasma zeaxanthin levels and reduced oxidative stress in middle-aged adults, emphasizing the fruit's antioxidant efficacy.
- https://www.explorationpub.com/Journals/eff/Article/101070 – Amagase et al. conducted a controlled study showing that *L. barbarum* juice improved immune function in older adults, marking increased lymphocyte and interleukin-2 levels as significant outcomes.
- https://saiie.co.za/sites/default/files/2023-10/ISEM%20PROCEEDINGS%202023_PV%20(1)_compressed.pdf – This proceeding outlines various aspects of *L. barbarum* research, highlighting its historical use and the breadth of ongoing studies evaluating its health benefits.
- https://www.mdpi.com/2673-9976/40/1/1 – The review identifies key compounds in goji berries and proposes avenues for future research, particularly focusing on long-term benefits and specific health implications.
Supplements Containing Goji Fruit Extract

Xphedrine Pro Diet
Quest Products

Malibu Miracle
Exotic OxyJuice

Joint Health
Emerald

B12 Energy
Windmill Natural Vitamins

OxyEnergy
Highland Laboratories

Stacked Greens Orchard Apple
Evlution Nutrition

Heart Healthy Multivitamin Complete
Dr. Sinatra

Mdrive Brain Chocolate Berry
DreamBrands

Mdrive Greens Chocolate Berry
DreamBrands
Acai Supreme
Nature's Answer

Men's Multivitamin
BioSchwartz

Women's Multivitamin
BioSchwartz
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